Targeting the gut microbiota-related metabolites for osteoporosis: the inextricable connection of gut-bone axis

YW Zhang, Y Wu, XF Liu, X Chen, JC Su - Ageing research reviews, 2024 - Elsevier
Osteoporosis is a systemic skeletal disease characterized by decreased bone mass,
destruction of bone microstructure, raised bone fragility, and enhanced risk of fractures. The …

Diets intervene osteoporosis via gut-bone axis

YW Zhang, PR Song, SC Wang, H Liu, ZM Shi… - Gut Microbes, 2024 - Taylor & Francis
Osteoporosis is a systemic skeletal disease that seriously endangers the health of middle-
aged and older adults. Recently, with the continuous deepening of research, an increasing …

Linking the relation between gut microbiota and glucocorticoid-induced osteoporosis

RX Zhou, YW Zhang, MM Cao, CH Liu, YF Rui… - Journal of Bone and …, 2023 - Springer
Osteoporosis (OP) is the most prevalent metabolic bone disease, characterized by the low
bone mass and microarchitectural deterioration of bone tissue. Glucocorticoid (GC) clinically …

Beneficial effect and mechanism of natural resourced polysaccharides on regulating bone metabolism through intestinal flora: A review

Y Zhou, YJ Sheng, CY Li, L Zou, CY Tong… - International Journal of …, 2023 - Elsevier
Bone metabolism is an important biological process for maintaining bone health.
Polysaccharides of natural origin exert beneficial effects on bone metabolism …

Cistanche deserticola improves ovariectomized-induced osteoporosis mainly by regulating lipid metabolism: Insights from serum metabolomics using UPLC/Q-TOF …

J Li, Z Zou, X Su, P Xu, H Du, Y Li, Z Li, L Guo… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Cistanche deserticola (C. deserticola) is an edible and
traditional medicine widely used in China, which has been confirmed to be effective in the …

Application of metabolomics in osteoporosis research

Z Zhao, Z Cai, A Chen, M Cai, K Yang - Frontiers in Endocrinology, 2022 - frontiersin.org
Osteoporosis (OP) is a systemic disease characterized by bone metabolism imbalance and
bone microstructure destruction, which causes serious social and economic burden. At …

Inulin Supplementation Modulates the Hepatic Transcriptome, Metabolome, and Ferritin Content in Ovariectomized Rats

X Zhao, W He, LMA Jakobsen… - Molecular Nutrition & …, 2023 - Wiley Online Library
Scope Liver is an important metabolic organ regulating whole‐body homeostasis. This study
aims to investigate how prebiotic‐induced changes in the metabolic activity of the gut …

Yogurt benefits bone mineralization in ovariectomized rats with concomitant modulation of the gut microbiome

W He, Z Xie, NK Wittig, LF Zachariassen… - Molecular Nutrition & …, 2022 - Wiley Online Library
Scope Evidence supports that gut‐modulating foods potentially can suppress bone loss in
postmenopausal women. This study aims to investigate the effect of milk calcium‐enriched …

NMR-based metabolomics to decipher the molecular mechanisms in the action of gut-modulating foods

W He, HC Bertram - Foods, 2022 - mdpi.com
Metabolomics deals with uncovering and characterizing metabolites present in a biological
system, and is a leading omics discipline as it provides the nearest link to the biological …

Influence of dairy matrix on the prebiotic effects of inulin related to gut metabolic activity and bone health

X Zhao, W He, LMA Jakobsen, FM Panah… - Food & Function, 2024 - pubs.rsc.org
Inulin is a well-recognized prebiotic ingredient established to modulate the gut microbiome
and its metabolic functionality. However, little is known about how the food matrix interacts …