Co-selection of multi-antibiotic resistance in bacterial pathogens in metal and microplastic contaminated environments: An emerging health threat

M Imran, KR Das, MM Naik - Chemosphere, 2019 - Elsevier
Misuse/over use of antibiotics increases the threats to human health since this is a main
reason behind evolution of antibiotic resistant bacterial pathogens. However, metals such as …

Using the class 1 integron-integrase gene as a proxy for anthropogenic pollution

MR Gillings, WH Gaze, A Pruden, K Smalla… - The ISME …, 2015 - academic.oup.com
Around all human activity, there are zones of pollution with pesticides, heavy metals,
pharmaceuticals, personal care products and the microorganisms associated with human …

Antibiotic resistome and its association with bacterial communities during sewage sludge composting

JQ Su, B Wei, WY Ou-Yang, FY Huang… - … science & technology, 2015 - ACS Publications
Composting is widely used for recycling of urban sewage sludge to improve soil properties,
which represents a potential pathway of spreading antibiotic resistant bacteria and genes to …

Integrons: past, present, and future

MR Gillings - Microbiology and molecular biology reviews, 2014 - Am Soc Microbiol
Integrons are versatile gene acquisition systems commonly found in bacterial genomes.
They are ancient elements that are a hot spot for genomic complexity, generating phenotypic …

Heavy metal driven co-selection of antibiotic resistance in soil and water bodies impacted by agriculture and aquaculture

C Seiler, TU Berendonk - Frontiers in microbiology, 2012 - frontiersin.org
The use of antibiotic agents as growth promoters was banned in animal husbandry to
prevent the selection and spread of antibiotic resistance. However, in addition to antibiotic …

[HTML][HTML] Heavy metal pollution and co-selection for antibiotic resistance: A microbial palaeontology approach

AW Dickinson, A Power, MG Hansen, KK Brandt… - Environment …, 2019 - Elsevier
Frequent and persistent heavy metal pollution has profound effects on the composition and
activity of microbial communities. Heavy metals select for metal resistance but can also co …

Gene flow, mobile genetic elements and the recruitment of antibiotic resistance genes into Gram-negative pathogens

HW Stokes, MR Gillings - FEMS microbiology reviews, 2011 - academic.oup.com
Antibiotics were one of the great discoveries of the 20th century. However, resistance
appeared even in the earliest years of the antibiotic era. Antibiotic resistance continues to …

A framework for standardized qPCR-targets and protocols for quantifying antibiotic resistance in surface water, recycled water and wastewater

I Keenum, K Liguori, J Calarco, BC Davis… - Critical Reviews in …, 2022 - Taylor & Francis
Water environments are increasingly recognized as a conduit for the spread of antibiotic
resistance, but there is need to standardize antibiotic resistance monitoring protocols to …

Integrons

G Cambray, AM Guerout, D Mazel - Annual review of genetics, 2010 - annualreviews.org
Integrons are genetic elements able to acquire and rearrange open reading frames (ORFs)
embedded in gene cassette units and convert them to functional genes by ensuring their …

Gene cassettes and cassette arrays in mobile resistance integrons

SR Partridge, G Tsafnat, E Coiera… - FEMS microbiology …, 2009 - academic.oup.com
Gene cassettes are small mobile elements, consisting of little more than a single gene and
recombination site, which are captured by larger elements called integrons. Several …