Collagen-and hyaluronic acid-based hydrogels and their biomedical applications

Q Xu, JE Torres, M Hakim, PM Babiak, P Pal… - Materials Science and …, 2021 - Elsevier
Hydrogels have been widely investigated in biomedical fields due to their similar physical
and biochemical properties to the extracellular matrix (ECM). Collagen and hyaluronic acid …

The content and size of hyaluronan in biological fluids and tissues

MK Cowman, HG Lee, KL Schwertfeger… - Frontiers in …, 2015 - frontiersin.org
Hyaluronan is a simple repeating disaccharide polymer, synthesized at the cell surface by
integral membrane synthases. The repeating sequence is perfectly homogeneous, and is …

The role of CD44 in disease pathophysiology and targeted treatment

AR Jordan, RR Racine, MJP Hennig… - Frontiers in …, 2015 - frontiersin.org
The cell-surface glycoprotein CD44 is involved in a multitude of important physiological
functions including cell proliferation, adhesion, migration, hematopoiesis, and lymphocyte …

[HTML][HTML] Recent advances and prospects of hyaluronan as a multifunctional therapeutic system

NG Kotla, SR Bonam, S Rasala, J Wankar… - Journal of Controlled …, 2021 - Elsevier
Hyaluronan (HA) is a naturally occurring non-sulfated glycosaminoglycan (GAG), cell-
surface-associated biopolymer and is the key component of tissue extracellular matrix …

Absorption, metabolism, and functions of hyaluronic acid and its therapeutic prospects in combination with microorganisms: A review

X Zheng, B Wang, X Tang, B Mao, Q Zhang… - Carbohydrate …, 2023 - Elsevier
Hyaluronic acid (HA) is key to the stability of the internal environment of tissues. HA content
in tissues gradually decreases with age, causing age-related health problems. Exogenous …

[HTML][HTML] Human milk components modulate toll-like receptor–mediated inflammation

YY He, NT Lawlor, DS Newburg - Advances in Nutrition, 2016 - Elsevier
Toll-like receptor (TLR) signaling is central to innate immunity. Aberrant expression of TLRs
is found in neonatal inflammatory diseases. Several bioactive components of human milk …

Utilization of Host-Derived Glycans by Intestinal Lactobacillus and Bifidobacterium Species

M Zúñiga, V Monedero, MJ Yebra - Frontiers in microbiology, 2018 - frontiersin.org
Members of the genus Lactobacillus are commonly found at the gastrointestinal tract and
other mucosal surfaces of humans. This genus includes various species with a great number …

Clinical applications of bioactive milk components

DR Hill, DS Newburg - Nutrition reviews, 2015 - academic.oup.com
Milk represents a unique resource for translational medicine: It contains a rich pool of
biologically active molecules with demonstrated clinical benefits. The ongoing …

The role of maternal breast milk in preventing infantile diarrhea in the developing world

CG Turin, TJ Ochoa - Current tropical medicine reports, 2014 - Springer
Multiple interventions have been designed to decrease mortality and disability in children.
Among these, breastfeeding is the most cost-effective intervention for protecting children …

Involvement of hyaluronan and CD44 in cancer and viral infections

P Heldin, C Kolliopoulos, CY Lin, CH Heldin - Cellular signalling, 2020 - Elsevier
Hyaluronan and its major receptor CD44 are ubiquitously distributed. They have important
structural as well as signaling roles, regulating tissue homeostasis, and their expression …