There exists a paucity of structural innovation and limited molecular diversity associated with
molecular frameworks in drug discovery and biomolecular imaging/chemical probe design …

Boron-containing compounds (BCC) have emerged as important pharmacophores. To date,
five BCC drugs (including boronic acids and boroles) have been approved by the FDA for …

Tuberculosis (TB) remains one of the most widespread and leading deadliest diseases,
threats one-third of the world's population. Although numerous efforts have been undertaken …

In this review, the history of boron's early use in drugs, and the history of the use of boron
functional groups in medicinal chemistry applications are discussed. This includes …

Boron cluster compounds are inorganic compounds with chemical compositions and
structures vastly different from those of organic compounds, albeit with the ability to form a …

A standard goal of medicinal chemists has been to discover efficient and potent drug
candidates with specific enzyme-inhibitor abilities. In this regard, boron-based bioactive …

The antiviral activity of nonfunctionalized gold nanoparticles (AuNPs) against herpes
simplex virus type-1 (HSV-1) in vitro was revealed in this study. We found that AuNPs are …

Data on compounds based on cage structures―boron clusters (polyhedral boron hydrides,
carboranes, metallacarboranes) and compounds of the adamantane series, which possess …

Carboranes are boron-rich molecular clusters possessing electronic characteristics that
allow for orthogonal approaches to vertex-selective modifications. We report improved …

Introduction: Icosahedral boron clusters have unique properties useful in medicinal
chemistry: rigidity, chemical stability, and three-dimensional aromaticity. Furthermore, these …