Potential therapeutic options for COVID-19: an update on current evidence
Abstract SARS-CoV-2, a novel coronavirus, is the agent responsible for the COVID-19
pandemic and is a major public health concern nowadays. The rapid and global spread of …
pandemic and is a major public health concern nowadays. The rapid and global spread of …
SARS-CoV-2 spike protein: pathogenesis, vaccines, and potential therapies
AM Almehdi, G Khoder, AS Alchakee, AT Alsayyid… - Infection, 2021 - Springer
Purpose COVID-19 pandemic has emerged as a result of infection by the deadly pathogenic
severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), causing enormous threats …
severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), causing enormous threats …
mRNA vaccines
Q Huang, J Zeng, JC Yan - J Genet Genomics, 2021 - cell.com
The Nobel Committee awarded the 2023 Prize for Physiology and Medicine to Drs. Katalin
Karikó and Drew Weissman “for their discoveries concerning nucleoside base modifications …
Karikó and Drew Weissman “for their discoveries concerning nucleoside base modifications …
Emergence of SARS-CoV-2 variants in the world: how could this happen?
A Parra-Lucares, P Segura, V Rojas, C Pumarino… - Life, 2022 - mdpi.com
The COVID-19 pandemic has had a significant global impact, with more than 280,000,000
people infected and 5,400,000 deaths. The use of personal protective equipment and the …
people infected and 5,400,000 deaths. The use of personal protective equipment and the …
An insight overview on COVID-19 mRNA vaccines: advantageous, pharmacology, mechanism of action, and prospective considerations
The worldwide spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
has urged scientists to present some novel vaccine platforms during this pandemic to …
has urged scientists to present some novel vaccine platforms during this pandemic to …
Nucleoside analogs and nucleoside precursors as drugs in the fight against SARS-CoV-2 and other coronaviruses
Coronaviruses (CoVs) are positive-sense RNA enveloped viruses, members of the family
Coronaviridae, that cause infections in a broad range of mammals including humans …
Coronaviridae, that cause infections in a broad range of mammals including humans …
What is holding back the development of antiviral metallodrugs? A literature overview and implications for SARS-CoV-2 therapeutics and future viral outbreaks
In light of the Covid-19 outbreak, this review brings together historical and current literature
efforts towards the development of antiviral metallodrugs. Classical compounds such as …
efforts towards the development of antiviral metallodrugs. Classical compounds such as …
In search of SARS CoV-2 replication inhibitors: virtual screening, molecular dynamics simulations and ADMET analysis
Severe acute respiratory syndrome has relapsed recently as novel coronavirus causing a
life threat to the entire world in the absence of an effective therapy. To hamper the replication …
life threat to the entire world in the absence of an effective therapy. To hamper the replication …
[HTML][HTML] Prevalence and predictors of in-hospital mortality of patients hospitalized with COVID-19 infection
F Khamis, Z Memish, M Al Bahrani, S Al Dowaiki… - Journal of infection and …, 2021 - Elsevier
Background The severity and mortality from COVID-19 infection vary among populations.
The aim of this study was to determine the prevalence and predictors of mortality among …
The aim of this study was to determine the prevalence and predictors of mortality among …
A comprehensive review of the clinical pharmacokinetics, pharmacodynamics, and drug interactions of nirmatrelvir/ritonavir
J Gerhart, DS Cox, RSP Singh, PLS Chan… - Clinical …, 2024 - Springer
Nirmatrelvir is a potent and selective inhibitor of the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) main protease that is used as an oral antiviral coronavirus …
coronavirus 2 (SARS-CoV-2) main protease that is used as an oral antiviral coronavirus …