The neuropsychiatry of Parkinson's disease: advances and challenges

D Weintraub, D Aarsland, KR Chaudhuri… - The Lancet …, 2022 - thelancet.com
In people with Parkinson's disease, neuropsychiatric signs and symptoms are common
throughout the disease course. These symptoms can be disabling and as clinically relevant …

[HTML][HTML] Dopamine agonists in Parkinson's disease: Impact of D1-like or D2-like dopamine receptor subtype selectivity and avenues for future treatment

SH Isaacson, RA Hauser, R Pahwa, D Gray… - Clinical parkinsonism & …, 2023 - Elsevier
Dopamine agonists (DAs) have demonstrated efficacy for the treatment of Parkinson's
disease (PD) but are limited by adverse effects (AEs). DAs can vary considerably in their …

Co-occurrence of apathy and impulse control disorders in Parkinson disease

BM Scott, RS Eisinger, MR Burns, J Lopes, MS Okun… - Neurology, 2020 - AAN Enterprises
Objective To empirically test whether apathy and impulse control disorders (ICDs) represent
independent, opposite ends of a motivational spectrum. Methods In this single-center, cross …

“He's Back so I'm Not Alone”: the impact of deep brain stimulation on personality, self, and relationships in Parkinson's disease

CJ Thomson, RA Segrave, E Racine… - Qualitative Health …, 2020 - journals.sagepub.com
Deep brain stimulation (DBS) for Parkinson's disease successfully alleviates motor
symptoms, but unanticipated changes in personality, self, and relationships can occur. Little …

The role of dopamine pharmacotherapy and addiction-like behaviors in Parkinson's disease

TC Napier, A Kirby, AL Persons - Progress in Neuro-Psychopharmacology …, 2020 - Elsevier
Addictions involve a spectrum of behaviors that encompass features of impulsivity and
compulsivity, herein referred to as impulsive-compulsive spectrum disorders (ICSDs). The …

Predictors of short-term impulsive and compulsive behaviour after subthalamic stimulation in Parkinson disease

A Sauerbier, P Loehrer, ST Jost, S Heil… - Journal of Neurology …, 2021 - jnnp.bmj.com
Background The effects of subthalamic stimulation (subthalamic nucleus-deep brain
stimulation, STN-DBS) on impulsive and compulsive behaviours (ICB) in Parkinson's …

Cholinergic receptor modulation as a target for preventing dementia in Parkinson's disease

A Iarkov, C Mendoza, V Echeverria - Frontiers in Neuroscience, 2021 - frontiersin.org
Parkinson's disease (PD) is a neurodegenerative condition characterized by the loss of
dopaminergic neurons in the substantia nigra pars compacta (SNpc) in the midbrain …

Predicting impulse control disorders in Parkinson disease through incentive biomarkers

J Marín‐Lahoz, S Martinez‐Horta… - Annals of …, 2022 - Wiley Online Library
Objective This study was undertaken to evaluate whether the feedback‐related negativity
(FRN)—a neurophysiological marker of incentive processing—can be used to predict the …

Should we start integrating genetic data in decision-making on device-aided therapies in Parkinson disease? A point of view

PA Salles, IF Mata, HH Fernandez - Parkinsonism & Related Disorders, 2021 - Elsevier
Parkinson disease (PD) is a complex heterogeneous neurodegenerative disorder.
Association studies have revealed numerous genetic risk loci and variants, and about 5 …

Impulse Control Disorders in the Polish Population of Patients with Parkinson's Disease

M Toś, A Grażyńska, S Antoniuk, J Siuda - Medicina, 2023 - mdpi.com
Background and Objectives: Parkinson's disease (PD) is one of the most common
neurodegenerative diseases in the world. It is characterized by the presence of not only …