Magnetic nanoparticles in targeted drug delivery: a review
E Kianfar - Journal of Superconductivity and Novel Magnetism, 2021 - Springer
Magnetic nanoparticles are one of the most important and widely used types of
nanomaterials, whose unique properties make them special compared to other …
nanomaterials, whose unique properties make them special compared to other …
Mechanistic landscape of membrane-permeabilizing peptides
Membrane permeabilizing peptides (MPPs) are as ubiquitous as the lipid bilayer
membranes they act upon. Produced by all forms of life, most membrane permeabilizing …
membranes they act upon. Produced by all forms of life, most membrane permeabilizing …
Mechanism matters: a taxonomy of cell penetrating peptides
The permeability barrier imposed by cellular membranes limits the access of exogenous
compounds to the interior of cells. Researchers and patients alike would benefit from …
compounds to the interior of cells. Researchers and patients alike would benefit from …
Cell-penetrating peptides transport therapeutics into cells
JD Ramsey, NH Flynn - Pharmacology & therapeutics, 2015 - Elsevier
Nearly 30 years ago, certain small, relatively nontoxic peptides were discovered to be
capable of traversing the cell membrane. These cell-penetrating peptides, as they are now …
capable of traversing the cell membrane. These cell-penetrating peptides, as they are now …
Engineering the drug carrier biointerface to overcome biological barriers to drug delivery
Micro and nanoscale drug carriers must navigate through a plethora of dynamic biological
systems prior to reaching their tissue or disease targets. The biological obstacles to drug …
systems prior to reaching their tissue or disease targets. The biological obstacles to drug …
Peptide-based strategies for enhanced cell uptake, transcellular transport, and circulation: Mechanisms and challenges
Peptides are emerging as a new tool in drug and gene delivery. Peptide-drug conjugates
and peptide-modified drug delivery systems provide new opportunities to avoid macrophage …
and peptide-modified drug delivery systems provide new opportunities to avoid macrophage …
[HTML][HTML] Peptide entry inhibitors of enveloped viruses: the importance of interfacial hydrophobicity
There are many peptides known that inhibit the entry of enveloped viruses into cells,
including one peptide that is successfully being used in the clinic as a drug. In this review …
including one peptide that is successfully being used in the clinic as a drug. In this review …
Transdermal gene delivery by functional peptide-conjugated cationic gold nanoparticle reverses the progression and metastasis of cutaneous melanoma
J Niu, Y Chu, YF Huang, YS Chong… - … applied materials & …, 2017 - ACS Publications
Permeability barrier imposed by stratum corneum makes an extreme challenge for the
topical delivery of plasmid DNA (pDNA), which is widely used in gene therapy. Existing …
topical delivery of plasmid DNA (pDNA), which is widely used in gene therapy. Existing …
Studies of cell-penetrating peptides by biophysical methods
M Zorko, Ü Langel - Quarterly Reviews of Biophysics, 2022 - cambridge.org
Biophysical studies have a very high impact on the understanding of internalization,
molecular mechanisms, interactions, and localization of CPPs and CPP/cargo conjugates in …
molecular mechanisms, interactions, and localization of CPPs and CPP/cargo conjugates in …
The role of molecular simulations in understanding the mechanisms of cell-penetrating peptides
Highlights•CPPs can partake in multiple cellular uptake mechanisms.•MD simulations can
be used to gain atomistic insight into CPP uptake mechanisms.•Biomolecular MD …
be used to gain atomistic insight into CPP uptake mechanisms.•Biomolecular MD …