The PSIPRED protein analysis workbench: 20 years on
DWA Buchan, DT Jones - Nucleic acids research, 2019 - academic.oup.com
The PSIPRED Workbench is a web server offering a range of predictive methods to the
bioscience community for 20 years. Here, we present the work we have completed to update …
bioscience community for 20 years. Here, we present the work we have completed to update …
Machine learning methods for protein structure prediction
Machine learning methods are widely used in bioinformatics and computational and
systems biology. Here, we review the development of machine learning methods for protein …
systems biology. Here, we review the development of machine learning methods for protein …
Bioinformatical approaches to characterize intrinsically disordered/unstructured proteins
Intrinsically disordered/unstructured proteins exist without a stable three-dimensional (3D)
structure as highly flexible conformational ensembles. The available genome sequences …
structure as highly flexible conformational ensembles. The available genome sequences …
Protein annotation and modelling servers at University College London
DWA Buchan, SM Ward, AE Lobley… - Nucleic acids …, 2010 - academic.oup.com
Abstract The UCL Bioinformatics Group web portal offers several high quality protein
structure prediction and function annotation algorithms including PSIPRED …
structure prediction and function annotation algorithms including PSIPRED …
A vaccine construction against COVID-19-associated mucormycosis contrived with immunoinformatics-based scavenging of potential Mucoralean Epitopes
Mucormycosis is a group of infections, caused by multiple fungal species, which affect many
human organs and is lethal in immunocompromised patients. During the COVID-19 …
human organs and is lethal in immunocompromised patients. During the COVID-19 …
Molecular architecture of the endocytic TPLATE complex
Eukaryotic cells rely on endocytosis to regulate their plasma membrane proteome and
lipidome. Most eukaryotic groups, except fungi and animals, have retained the evolutionary …
lipidome. Most eukaryotic groups, except fungi and animals, have retained the evolutionary …
The use of systematic N-and C-terminal deletions to promote production and structural studies of recombinant proteins
S Gräslund, J Sagemark, H Berglund… - Protein expression and …, 2008 - Elsevier
Bacterial over-expression of proteins is a powerful tool to obtain soluble protein amenable to
biochemical, biophysical and/or structural characterization. However, it is well established …
biochemical, biophysical and/or structural characterization. However, it is well established …
Molecular architecture and function of the SEA complex, a modulator of the TORC1 pathway
The TORC1 signaling pathway plays a major role in the control of cell growth and response
to stress. Here we demonstrate that the SEA complex physically interacts with TORC1 and is …
to stress. Here we demonstrate that the SEA complex physically interacts with TORC1 and is …
Automated server predictions in CASP7
With each round of CASP (Critical Assessment of Techniques for Protein Structure
Prediction), automated prediction servers have played an increasingly important role. Today …
Prediction), automated prediction servers have played an increasingly important role. Today …
Modular prediction of protein structural classes from sequences of twilight-zone identity with predicting sequences
MJ Mizianty, L Kurgan - BMC bioinformatics, 2009 - Springer
Background Knowledge of structural class is used by numerous methods for identification of
structural/functional characteristics of proteins and could be used for the detection of remote …
structural/functional characteristics of proteins and could be used for the detection of remote …