This review summarises genetic studies in which calcium channel genes have been
connected to the spectrum of neuropsychiatric syndromes, from bipolar disorder and …

Mental health and social life are intimately inter-related, as demonstrated by the frequent
social deficits of psychiatric patients and the increased rate of psychiatric disorders in people …

BACKGROUND: Findings from family and twin studies suggest that genetic contributions to
psychiatric disorders do not in all cases map to present diagnostic categories. We aimed to …

We conducted a combined genome-wide association study (GWAS) of 7,481 individuals
with bipolar disorder (cases) and 9,250 controls as part of the Psychiatric GWAS …

Characterizing the brain connectome using neuroimaging data and measures derived from
graph theory emerged as a new approach that has been applied to brain maturation …

A large portion of common variant loci associated with genetic risk for schizophrenia reside
within noncoding sequence of unknown function. Here, we demonstrate promoter and …

One of the most consistent genetic findings to have emerged from bipolar disorder genome
wide association studies (GWAS) is with CACNA1C, a gene that codes for the α1C subunit …

Given the manifold ways that depression impairs Darwinian fitness, the persistence in the
human genome of risk alleles for the disorder remains a much debated mystery …

Functional and structural brain imaging has identified neural and neurotransmitter systems
involved in schizophrenia and their link to cognitive and behavioural disturbances such as …

Single-nucleotide polymorphisms (SNPs) in CACNA1C, the α1C subunit of the voltage-
gated L-type calcium channel Ca v 1.2, rank among the most consistent and replicable …