MMP13 polymorphism decreases risk for dental caries

PN Tannure, EC Küchler, P Falagan-Lotsch… - Caries …, 2012 - karger.com
Recent evidence suggests that genetic studies may contribute to a better understanding of
individual susceptibility to caries. Matrix metalloproteinases (MMPs) and their tissue …

Mg–Al and Zn–Al layered double hydroxides promote dynamic expression of marker genes in osteogenic differentiation by Modulating Mitogen‐Activated Protein …

HR Kang, CJ da Costa Fernandes… - Advanced …, 2018 - Wiley Online Library
The effect of LDH samples comprised of chloride anions intercalated between positive
layers of magnesium/aluminum (Mg‐Al LDH) or zinc/aluminum (Zn‐Al LDH) chemical …

Nanohydroxyapatite‐blasted bioactive surface drives shear‐stressed endothelial cell growth and angiogenesis

TS Pinto, BR Martins, MR Ferreira… - BioMed Research …, 2022 - Wiley Online Library
Nanosized crystalline hydroxyapatite coating (HAnano®) accelerates the osteointegration of
dental implants which is hypothesized to drive angiogenesis. In order to test this hypothesis …

Fibroblast-secreted trophic factors contribute with ECM remodeling stimulus and upmodulate osteocyte gene markers in osteoblasts

WF Zambuzzi - Biochimie, 2020 - Elsevier
As osteogenesis is a multifactorial mechanism, we wonder whether osteoblast-induced
extracellular matrix (ECM) remodeling might be modulated by trophic factors released by …

Binding of amelogenin to MMP-9 and their co-expression in developing mouse teeth

J Feng, JS McDaniel, HH Chuang, O Huang… - Journal of molecular …, 2012 - Springer
Amelogenin is the most abundant matrix protein in enamel. Proper amelogenin processing
by proteinases is necessary for its biological functions during amelogenesis. Matrix …

MMP-9 and CD68+ cells are required for tissue remodeling in response to natural hydroxyapatite

WF Zambuzzi, KBS Paiva, R Menezes… - Journal of molecular …, 2009 - Springer
Large bone defects represent major clinical problems in the practice of reconstructive
orthopedic and craniofacial surgery. The aim of this study was to examine, through …

Development of secondary palate requires strict regulation of ECM remodeling: sequential distribution of RECK, MMP-2, MMP-3, and MMP-9

ACC de Oliveira Demarchi, WF Zambuzzi… - Cell and tissue …, 2010 - Springer
We have evaluated RECK (reversion-inducing-cysteine-rich protein with Kazal motifs), MMP-
2 (matrix metalloproteinase-2), MMP-3, and MMP-9 involvement during palate development …

Phosphoproteome analysis reveals a critical role for hedgehog signalling in osteoblast morphological transitions

A Marumoto, R Milani, RA da Silva… - Bone, 2017 - Elsevier
The reciprocal and adaptive interactions between cells and substrates governing
morphological transitions in the osteoblast compartment remain largely obscure. Here we …

Modulatory effects of silibinin in cell behavior during osteogenic phenotype

CJC Fernandes, MR Veiga… - Journal of Cellular …, 2019 - Wiley Online Library
Natural molecules, such as flavonoid, are very welcome strategies to modulate bone
turnover. This prompted us to comprehend better the effect of silibinin on osteoblast …

Mechanosignaling-related angiocrine factors drive osteoblastic phenotype in response to zirconia

CJC Fernandes, GS de Almeida, PF Wood… - Journal of Trace …, 2024 - Elsevier
Background The growing use of zirconia as a ceramic material in dentistry is attributed to its
biocompatibility, mechanical properties, esthetic appearance, and reduced bacterial …