[HTML][HTML] Neutrophil to lymphocyte ratio and cancer prognosis: an umbrella review of systematic reviews and meta-analyses of observational studies
Background Although neutrophils have been linked to the progression of cancer, uncertainty
exists around their association with cancer outcomes, depending on the site, outcome and …
exists around their association with cancer outcomes, depending on the site, outcome and …
[HTML][HTML] Application of the CRISPR/Cas9-based gene editing technique in basic research, diagnosis, and therapy of cancer
H Zhang, C Qin, C An, X Zheng, S Wen, W Chen, X Liu… - Molecular cancer, 2021 - Springer
Abstract The 2020 Nobel Prize in Chemistry was awarded to Emmanuelle Charpentier and
Jennifer Doudna for the development of the Clustered regularly interspaced short …
Jennifer Doudna for the development of the Clustered regularly interspaced short …
[HTML][HTML] Exaggerated false positives by popular differential expression methods when analyzing human population samples
When identifying differentially expressed genes between two conditions using human
population RNA-seq samples, we found a phenomenon by permutation analysis: two …
population RNA-seq samples, we found a phenomenon by permutation analysis: two …
[HTML][HTML] RNA-Seq differential expression analysis: An extended review and a software tool
The correct identification of differentially expressed genes (DEGs) between specific
conditions is a key in the understanding phenotypic variation. High-throughput transcriptome …
conditions is a key in the understanding phenotypic variation. High-throughput transcriptome …
[HTML][HTML] Translating RNA sequencing into clinical diagnostics: opportunities and challenges
SA Byron, KR Van Keuren-Jensen… - Nature Reviews …, 2016 - nature.com
With the emergence of RNA sequencing (RNA-seq) technologies, RNA-based biomolecules
hold expanded promise for their diagnostic, prognostic and therapeutic applicability in …
hold expanded promise for their diagnostic, prognostic and therapeutic applicability in …
Immune responses during COVID-19 infection
C Melenotte, A Silvin, AG Goubet, I Lahmar… - …, 2020 - Taylor & Francis
Over the past 16 years, three coronaviruses (CoVs), severe acute respiratory syndrome CoV
(SARS-CoV) in 2002, Middle East respiratory syndrome CoV (MERS-CoV) in 2012 and …
(SARS-CoV) in 2002, Middle East respiratory syndrome CoV (MERS-CoV) in 2012 and …
Challenges and best practices in omics benchmarking
TG Brooks, NF Lahens, A Mrčela, GR Grant - Nature Reviews Genetics, 2024 - nature.com
Technological advances enabling massively parallel measurement of biological features—
such as microarrays, high-throughput sequencing and mass spectrometry—have ushered in …
such as microarrays, high-throughput sequencing and mass spectrometry—have ushered in …
[HTML][HTML] VIPER: Visualization Pipeline for RNA-seq, a Snakemake workflow for efficient and complete RNA-seq analysis
Background RNA sequencing has become a ubiquitous technology used throughout life
sciences as an effective method of measuring RNA abundance quantitatively in tissues and …
sciences as an effective method of measuring RNA abundance quantitatively in tissues and …
Molecular intrinsic versus clinical subtyping in breast cancer: A comprehensive review
A Szymiczek, A Lone, MR Akbari - Clinical genetics, 2021 - Wiley Online Library
Breast cancer is a heterogeneous disease manifesting diversity at the molecular,
histological and clinical level. The development of breast cancer classification was centered …
histological and clinical level. The development of breast cancer classification was centered …
[HTML][HTML] Trimming of sequence reads alters RNA-Seq gene expression estimates
Abstract Background High-throughput RNA-Sequencing (RNA-Seq) has become the
preferred technique for studying gene expression differences between biological samples …
preferred technique for studying gene expression differences between biological samples …