The striatal dopamine system has long been studied in the context of reward learning,
motivation, and movement. Given the prominent role dopamine plays in a variety of adaptive …

Fiber photometry enables recording of population neuronal calcium dynamics in awake
mice. While the popularity of fiber photometry has grown in recent years, it remains unclear …

Significant evidence supports the view that dopamine shapes learning by encoding reward
prediction errors. However, it is unknown whether striatal targets receive tailored dopamine …

Dopamine (DA) neuron projections to the striatum are functionally heterogeneous with
diverse behavioral roles. We focus here on DA neuron projections to the nucleus …

Striatal dopamine encodes reward, with recent work showing that dopamine release occurs
in spatiotemporal waves. However, the mechanism of dopamine waves is unknown. Here …

Motivation to work for potential rewards is critically dependent on dopamine (DA) in the
nucleus accumbens (NAc). DA release from NAc axons can be controlled by at least two …

Striatal acetylcholine and dopamine critically regulate movement, motivation, and reward-
related learning. Pauses in cholinergic interneuron (CIN) firing are thought to coincide with …

Interplay between dopaminergic and cholinergic neuromodulation in the striatum is crucial
for movement control, with prominent models proposing pro-kinetic and anti-kinetic effects of …

Environmental cues, through Pavlovian learning, become conditioned stimuli that invigorate
and guide animals toward rewards. Dopamine (DA) neurons in the ventral tegmental area …

Striatal cholinergic interneurons (CINs) are the main source of acetylcholine in the striatum
and are believed to play an important role in basal ganglia physiology and pathophysiology …