EARLY efforts to purify a bone-derived growth factor from rat bone culture medium revealed
its biological and biochemical similarity to transforming growth factor-β type 1 (TGF-β1) …

The organic matrix of bone contains several protein families, including collagens,
proteoglycans, and glycoproteins, all of which may be extensively modified by …

Osteochondral progenitor cells were used to repair large, full-thickness defects of the
articular cartilage that had been created in the knees of rabbits. Adherent cells from bone …

Bone morphogenetic protein 2 (BMP‐2) plays a decisive role during bone regeneration and
repair as well as during various stages of embryonal development. A cDNA encoding …

Biodegradable materials for spatially and temporally controlled delivery of bioactive agents
such as drugs, growth factors, or cytokines are key to facilitating tissue repair. We have …

Titanium (Ti) surface roughness affects proliferation, differentiation, and matrix production of
MG‐63 osteoblast‐like cells. Cytokines and growth factors produced in the milieu …

The objective of the study presented here was to investigate the bone inductive properties
as well as release kinetics of rhTGF-β1-and rhBMP-2-loaded Ti-fiber mesh and CaP cement …

Bovine cornea contains three unique keratan sulfate proteoglycans (KSPGs), of which two
(lumican and keratocan) have been characterized using molecular cloning. The gene for the …

The skeleton serves as an internal structural support system for vertebrates. It has
mechanisms to grow and change in shape and size to suit varying stressors including the …

PROGRESS IN SCIENCE appears part and parcel with the introduction of new experimental
methods. Three landmarks in the history of experimental embryology emerged from new …