Alzheimer's disease (AD) is the leading cause of dementia in elderly people. Amyloid beta
(Aβ) deposits and neurofibrillary tangles are the major pathological features in an …

Alzheimer's disease (AD) is a progressive, mental illness without cure. Several years of
intense research on postmortem AD brains, cell and mouse models of AD have revealed …

The clinical efficacy and safety of a drug is determined by its molecular properties and
targets in humans. However, proteome-wide evaluation of all compounds in humans, or …

Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by
memory loss and multiple cognitive impairments. AD is marked by multiple cellular changes …

The purpose of our study is to determine the protective effects of mitophagy enhancers
against phosphorylated tau (P-tau)-induced mitochondrial and synaptic toxicities in …

Alzheimer's disease (AD) is recognized as a major health hazard that mostly affects people
older than 60 years. AD is one of the biggest medical, economic, and social concerns to …

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive
cognitive decline, amyloid-β (Aβ) plaques and the formation of neurofibrillary tangles (NFTs) …

The purpose of our study is to identify phosphorylated tau (p-tau) inhibitors. P-tau has
recently received great interest as a potential drug target in Alzheimer's disease (AD). The …

Activating transcription factors, ATFs, is a family of transcription factors that activate gene
expression and transcription by recognizing and combining the cAMP response element …

Tau is a microtubule-stabilizing protein that plays an important role in the formation of axonal
microtubules in neurons. Phosphorylated tau (p-Tau) has received great attention in the field …