Rheumatoid arthritis is a systemic autoimmune disease characterized by excess morbidity
and mortality from cardiovascular disease. Mechanisms linking rheumatoid arthritis and …

A variety of systemic inflammatory rheumatic diseases associate with an increased risk of
atherosclerotic events and premature cardiovascular (CV) disease. Although this recognition …

Here we identify hundreds of new drug-disease associations for over 900 FDA-approved
drugs by quantifying the network proximity of disease genes and drug targets in the human …

Introduction: There is a growing body of evidence to suggest that chronic silent inflammation
is a key feature in abdominal obesity, metabolic syndrome, type 2 diabetes (T2DM) and …

The systemic autoimmune disease rheumatoid arthritis (RA) is characterized by increased
cardiovascular mortality and morbidity and is an independent cardiovascular risk factor …

Civilization diseases are defined as non-communicable diseases that affect a large part of
the population. Examples of such diseases are depression and cardiovascular disease …

A better understanding about the mechanisms involved in the pathogenesis of type 2
diabetes mellitus (T2D) showed that inflammatory cytokines such as tumour necrosis factor …

Rheumatoid arthritis (RA) is associated with increased cardiovascular (CV) morbidity and
mortality which cannot be fully explained by traditional CV risk factors; cumulative …

Rheumatoid arthritis (RA) has been associated with endothelial dysfunction, a
pathophysiological feature of atherosclerosis. Our aim was to determine whether TNF-α …

Longer life span and increased prevalence of chronic, noncommunicable, inflammatory
diseases fuel cardiovascular mortality. The microcirculation is central in the cross talk …