The epidemiology of Alzheimer's disease modifiable risk factors and prevention

XX Zhang, Y Tian, ZT Wang, YH Ma, L Tan… - The journal of prevention …, 2021 - Springer
Mild Alzheimer's disease is the leading cause of dementia, accounting for 50–70% of cases.
Alzheimer's disease is an irreversible neurodegenerative disease, which affects daily life …

[HTML][HTML] Past, present and future of therapeutic strategies against amyloid-β peptides in Alzheimer's disease: A systematic review

D Jeremic, L Jiménez-Díaz, JD Navarro-López - Ageing research reviews, 2021 - Elsevier
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in ageing,
affecting around 46 million people worldwide but few treatments are currently available. The …

Passage of exogeneous fine particles from the lung into the brain in humans and animals

Y Qi, S Wei, T Xin, C Huang, Y Pu… - Proceedings of the …, 2022 - National Acad Sciences
There are still significant knowledge gaps in understanding the intrusion and retention of
exogeneous particles into the central nervous system (CNS). Here, we uncovered various …

A national cohort study (2000–2018) of long-term air pollution exposure and incident dementia in older adults in the United States

L Shi, K Steenland, H Li, P Liu, Y Zhang… - Nature …, 2021 - nature.com
Air pollution may increase risk of Alzheimer's disease and related dementias (ADRD) in the
US, but the extent of this relationship is unclear. Here, we constructed two national US …

Gene–environment interactions in Alzheimer disease: the emerging role of epigenetics

L Migliore, F Coppedè - Nature Reviews Neurology, 2022 - nature.com
With the exception of a few monogenic forms, Alzheimer disease (AD) has a complex
aetiology that is likely to involve multiple susceptibility genes and environmental factors. The …

The impact of exposure to air pollution on cognitive performance

X Zhang, X Chen, X Zhang - Proceedings of the National …, 2018 - National Acad Sciences
This paper examines the effect of both cumulative and transitory exposures to air pollution
for the same individuals over time on cognitive performance by matching a nationally …

The Lancet Commission on pollution and health

PJ Landrigan, R Fuller, NJR Acosta, O Adeyi, R Arnold… - The lancet, 2018 - thelancet.com
Executive summary Pollution is the largest environmental cause of disease and premature
death in the world today. Diseases caused by pollution were responsible for an estimated 9 …

[HTML][HTML] Long-term effects of PM2· 5 on neurological disorders in the American Medicare population: a longitudinal cohort study

L Shi, X Wu, MD Yazdi, D Braun, YA Awad… - The Lancet Planetary …, 2020 - thelancet.com
Background Accumulating evidence links fine particulate matter (PM 2· 5) to premature
mortality, cardiovascular disease, and respiratory disease. However, less is known about the …

A comprehensive understanding of ambient particulate matter and its components on the adverse health effects based from epidemiological and laboratory evidence

T Li, Y Yu, Z Sun, J Duan - Particle and fibre toxicology, 2022 - Springer
The impacts of air pollution on public health have become a great concern worldwide.
Ambient particulate matter (PM) is a major air pollution that comprises a heterogeneous …

Dementia prevention, intervention, and care

G Livingston, A Sommerlad, V Orgeta, SG Costafreda… - The lancet, 2017 - thelancet.com
Executive summary Acting now on dementia prevention, intervention, and care will vastly
improve living and dying for individuals with dementia and their families, and in doing so …