It has been proposed that a chronic state of inflammation correlated with aging known as
inflammaging, is implicated in multiple disease states commonly observed in the elderly …

Alzheimer's disease (AD) is a neurodegenerative disease associated with human aging.
Ten percent of individuals over 65 years have AD and its prevalence continues to rise with …

Increasing evidence indicates that alterations in gut microbiota are associated with
mammalian development and physiology. The gut microbiota has been proposed as an …

Object To evaluate the clinical efficacy and safety of α-Lipoic acid (ALA) for critically ill
patients with coronavirus disease 2019 (COVID-19). Methods A randomized, single-blind …

Alzheimer's disease (AD) is a neurodegenerative disorder characterised by impairments in
the cognitive domains associated with orientation, recording, and memory. This pathology …

Oxidative stress, characterized by excessive accumulation of reactive oxygen species
(ROS), is involved in acute myocardial infarction (AMI)-related pathological processes and …

The amyloid hypothesis, the assumption that beta-amyloid toxicity is the primary cause of
neuronal and synaptic loss, has been the mainstream research concept in Alzheimer's …

Background: Diabetes is a multifactorial disease and a major cause for many microvascular
and macrovascular complications. The disease will ultimately lead to high rate mortality if it …

ARG2 has been reported to inhibit autophagy in vascular endothelial cells and
keratinocytes. However, studies of its mechanism of action, its role in skin fibroblasts, and …

Glycation refers to carbonyl group condensation of the reducing sugar with the free amino
group of protein, which forms Amadori products and advanced glycation end products …