Imaging collagen in scar tissue: developments in second harmonic generation microscopy for biomedical applications
The ability to respond to injury with tissue repair is a fundamental property of all multicellular
organisms. The extracellular matrix (ECM), composed of fibrillar collagens as well as a …
organisms. The extracellular matrix (ECM), composed of fibrillar collagens as well as a …
Label-free multiphoton microscopy: much more than fancy images
Multiphoton microscopy has recently passed the milestone of its first 30 years of activity in
biomedical research. The growing interest around this approach has led to a variety of …
biomedical research. The growing interest around this approach has led to a variety of …
Optical microscopy and the extracellular matrix structure: a review
JJA Poole, LB Mostaço-Guidolin - Cells, 2021 - mdpi.com
Biological tissues are not uniquely composed of cells. A substantial part of their volume is
extracellular space, which is primarily filled by an intricate network of macromolecules …
extracellular space, which is primarily filled by an intricate network of macromolecules …
Defective fibrillar collagen organization by fibroblasts contributes to airway remodeling in asthma
LB Mostaço-Guidolin, ET Osei, J Ullah… - American journal of …, 2019 - atsjournals.org
Rationale: Histologic stains have been used as the gold standard to visualize extracellular
matrix (ECM) changes associated with airway remodeling in asthma, yet they provide no …
matrix (ECM) changes associated with airway remodeling in asthma, yet they provide no …
Collagen morphology and texture analysis: from statistics to classification
In this study we present an image analysis methodology capable of quantifying
morphological changes in tissue collagen fibril organization caused by pathological …
morphological changes in tissue collagen fibril organization caused by pathological …
Kerr-lens mode locking of a diode-pumped Yb: KGW laser using an additional intracavity Kerr medium
R Akbari, A Major - Laser Physics Letters, 2018 - iopscience.iop.org
Kerr-lens mode-locked operation of a Yb: KGW laser pumped by a multimode laser diode
with the help of an additional Kerr medium is reported. With an enhanced Kerr lensing effect …
with the help of an additional Kerr medium is reported. With an enhanced Kerr lensing effect …
High power continuous-wave dual-wavelength alexandrite laser
S Ghanbari, A Major - Laser Physics Letters, 2017 - iopscience.iop.org
A high power dual-wavelength alexandrite (Cr: BeAl 2 O 4) laser using a single plate
birefringent filter (BRF) was demonstrated. Using a 6 mm thick BRF, dual-wavelength output …
birefringent filter (BRF) was demonstrated. Using a 6 mm thick BRF, dual-wavelength output …
Machine learning-enabled cancer diagnostics with widefield polarimetric second-harmonic generation microscopy
K Mirsanaye, L Uribe Castaño, Y Kamaliddin… - Scientific reports, 2022 - nature.com
The extracellular matrix (ECM) collagen undergoes major remodeling during tumorigenesis.
However, alterations to the ECM are not widely considered in cancer diagnostics, due to …
However, alterations to the ECM are not widely considered in cancer diagnostics, due to …
High-power diode-pumped Kerr-lens mode-locked bulk Yb: KGW laser
R Akbari, A Major - Applied Optics, 2017 - opg.optica.org
A high-power (> 1 W) pure Kerr-lens mode-locked bulk Yb: KGW laser with multimode fiber-
coupled diode pumping was demonstrated. The laser delivered 240 fs pulses with 2.3 W of …
coupled diode pumping was demonstrated. The laser delivered 240 fs pulses with 2.3 W of …
Unsupervised determination of lung tumor margin with widefield polarimetric second-harmonic generation microscopy
K Mirsanaye, L Uribe Castaño, Y Kamaliddin… - Scientific Reports, 2022 - nature.com
The extracellular matrix (ECM) is amongst many tissue components affected by cancer,
however, morphological changes of the ECM are not well-understood and thus, often …
however, morphological changes of the ECM are not well-understood and thus, often …