Vascular endothelial cells: heterogeneity and targeting approaches

JK Hennigs, C Matuszcak, M Trepel, J Körbelin - Cells, 2021 - mdpi.com
Forming the inner layer of the vascular system, endothelial cells (ECs) facilitate a multitude
of crucial physiological processes throughout the body. Vascular ECs enable the vessel wall …

Angiocrine functions of organ-specific endothelial cells

S Rafii, JM Butler, BS Ding - Nature, 2016 - nature.com
Endothelial cells that line capillaries are not just passive conduits for delivering blood.
Tissue-specific endothelium establishes specialized vascular niches that deploy sets of …

Generation of vascularized brain organoids to study neurovascular interactions

XY Sun, XC Ju, Y Li, PM Zeng, J Wu, YY Zhou… - elife, 2022 - elifesciences.org
Brain organoids have been used to recapitulate the processes of brain development and
related diseases. However, the lack of vasculatures, which regulate neurogenesis and brain …

[HTML][HTML] Targeted delivery of neural progenitor cell-derived extracellular vesicles for anti-inflammation after cerebral ischemia

T Tian, L Cao, C He, Q Ye, R Liang, W You, H Zhang… - Theranostics, 2021 - ncbi.nlm.nih.gov
Ischemic stroke remains a major cause of death, and anti-inflammatory strategies hold great
promise for preventing major brain injury during reperfusion. In the past decade, stem cell …

RGD engineered dendrimer nanotherapeutic as an emerging targeted approach in cancer therapy

A Sheikh, S Md, P Kesharwani - Journal of Controlled Release, 2021 - Elsevier
A bird's eye view is now demanded in the area of cancer research to suppress the suffering
of cancer patient and mediate the lack of treatment related to chemotherapy. Chemotherapy …

Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells

ES Lippmann, SM Azarin, JE Kay, RA Nessler… - Nature …, 2012 - nature.com
The blood-brain barrier (BBB) is crucial to the health of the brain and is often compromised
in neurological disease. Moreover, because of its barrier properties, this endothelial …

Dendrimers designed for functions: from physical, photophysical, and supramolecular properties to applications in sensing, catalysis, molecular electronics, photonics …

D Astruc, E Boisselier, C Ornelas - Chemical reviews, 2010 - ACS Publications
Dendrimers Designed for Functions: From Physical, Photophysical, and Supramolecular
Properties to Applications in Sensing, Catalysis, Molecular Electronics, Photonics, and …

Cancer associated fibroblasts: the architects of stroma remodeling

A Santi, FG Kugeratski, S Zanivan - Proteomics, 2018 - Wiley Online Library
Fibroblasts have exceptional phenotypic plasticity and capability to secrete vast amount of
soluble factors, extracellular matrix components and extracellular vesicles. While in …

Angiogenesis in health and disease

P Carmeliet - Nature medicine, 2003 - nature.com
Blood vessels constitute the first organ in the embryo and form the largest network in our
body but, sadly, are also often deadly. When dysregulated, the formation of new blood …

[HTML][HTML] Habitual use of vitamin D supplements and risk of coronavirus disease 2019 (COVID-19) infection: a prospective study in UK Biobank

H Ma, T Zhou, Y Heianza, L Qi - The American journal of clinical nutrition, 2021 - Elsevier
Background Previous studies have related vitamin D supplementation to a lower risk of
acute respiratory tract infection. Emerging evidence suggests that vitamin D insufficiency is …