The biological effects of cannabinoids, the major constituents of the ancient medicinal plant
Cannabis sativa (marijuana) are mediated by two members of the G-protein coupled …

Astrocytes serve important roles that affect recruitment and function of neurons at the local
and network levels. Here we review the contributions of astrocyte signaling to synaptic …

Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …

Astrocytes take up glucose from the bloodstream to provide energy to the brain, thereby
allowing neuronal activity and behavioural responses,,,–. By contrast, astrocytes are under …

Astrocytes respond to neuronal activity and were shown to be necessary for plasticity and
memory. To test whether astrocytic activity is also sufficient to generate synaptic potentiation …

The endocannabinoid system (ECS) is a widespread neuromodulatory system that plays
important roles in central nervous system development, synaptic plasticity, and the response …

Astrocytes are emerging as important players in synaptic function, and, consequently, on
brain function and animal behavior. According to the Tripartite Synapse concept, astrocytes …

In the hippocampus GABAergic local circuit inhibitory interneurons represent only~ 10–15%
of the total neuronal population; however, their remarkable anatomical and physiological …

Apart from having been used and misused for at least four millennia for, among others,
recreational and medicinal purposes, the cannabis plant and its most peculiar chemical …

Astrocytes are highly complex cells with many emerging putative roles in brain function. Of
these, gliotransmission (active information transfer from glia to neurons) has probably the …