Tryptophan synthase is a pyridoxal 5′-phosphate-dependent α 2 β 2 complex catalyzing
the last two steps of tryptophan biosynthesis in bacteria, plants and fungi. Structural …

Human serine racemase is a pyridoxal 5′-phosphate (PLP)-dependent dimeric enzyme
that catalyzes the reversible racemization of L-serine and D-serine and their dehydration to …

Several enzymes have evolved as sensors in signal transduction pathways to control gene
expression, thereby allowing bacteria to adapt efficiently to environmental changes. We …

The last step of cysteine biosynthesis in bacteria and plants is catalyzed by O-acetylserine
sulfhydrylase. In bacteria, two isozymes, O-acetylserine sulfhydrylase-A and O-acetylserine …

Abstract Pyridoxal 5′‐phosphate (PLP)‐dependent enzymes represent about 4% of the
enzymes classified by the Enzyme Commission. The versatility of PLP in carrying out a large …

Pseudomonas putida L-methionine γ-lyase (PpMGL) has been recognized as an efficient
anticancer agent, however, its antigenicity and stability remain as critical challenges for its …

Cystathionine γ-lyase (CGL) is a key enzyme in the methionine–cysteine cycle in all living
organisms forming cysteine, α-ketobutyrate and ammonia via homocysteine and …

Infectious diseases have been jeopardized problem that threaten public health over a long
period of time. The growing prevalence of drug‐resistant pathogens and infectious cases …

In humans, the phosphorylated pathway (PP) converts the glycolytic intermediate D-3-
phosphoglycerate (3-PG) into L-serine through the enzymes 3-phosphoglycerate …

Cysteine is a building block for several biomolecules that are crucial for living organisms.
The last step of cysteine biosynthesis is catalyzed by O-acetylserine sulfydrylase (OASS), a …