A review of proton therapy–Current status and future directions

R Mohan - Precision radiation oncology, 2022 - Wiley Online Library
The original rationale for proton therapy was its highly conformal depth‐dose distributions
compared to photons, which allow greater sparing of normal tissues and escalation of tumor …

Roadmap: proton therapy physics and biology

H Paganetti, C Beltran, S Both, L Dong… - Physics in Medicine …, 2021 - iopscience.iop.org
The treatment of cancer with proton radiation therapy was first suggested in 1946 followed
by the first treatments in the 1950s. As of 2020, almost 200 000 patients have been treated …

Adaptive radiation therapy in the treatment of lung cancer: An overview of the current state of the field

H Piperdi, D Portal, SS Neibart, NJ Yue… - Frontiers in …, 2021 - frontiersin.org
Lung cancer treatment is constantly evolving due to technological advances in the delivery
of radiation therapy. Adaptive radiation therapy (ART) allows for modification of a treatment …

AAPM Task Group Report 290: Respiratory motion management for particle therapy

H Li, L Dong, C Bert, J Chang, S Flampouri… - Medical …, 2022 - Wiley Online Library
Dose uncertainty induced by respiratory motion remains a major concern for treating
thoracic and abdominal lesions using particle beams. This Task Group report reviews the …

Charged particle beams to cure cancer: strengths and challenges

M Durante, J Flanz - Seminars in oncology, 2019 - Elsevier
Charged particle therapy is the most advanced radiotherapy method in oncology. The
favorable depth-dose distribution and the biological properties of charged particles have …

Substantial sparing of organs at risk with modern proton therapy in lung cancer, but altered breathing patterns can jeopardize target coverage

CG Boer, K Fjellanger, IM Sandvik, M Ugland… - Cancers, 2022 - mdpi.com
Simple Summary Treatment of locally advanced non-small cell lung cancer (LA-NSCLC) is a
fine balance between toxicity and cure. Modern proton therapy might offer a more gentle …

Anatomic change over the course of treatment for non–small cell lung cancer patients and its impact on intensity-modulated radiation therapy and passive-scattering …

M Chen, J Yang, Z Liao, J Chen, C Xu, X He… - Radiation …, 2020 - Springer
Purpose To quantify tumor anatomic change of non-small cell lung cancer (NSCLC) patients
given passive-scattering proton therapy (PSPT) and intensity-modulated radiation therapy …

[HTML][HTML] Early outcomes of patients with locally advanced non-small cell lung cancer treated with intensity-modulated proton therapy versus intensity-modulated …

YY Nathan, TA DeWees, C Liu, TB Daniels… - Advances in Radiation …, 2020 - Elsevier
Purpose There are very little data available comparing outcomes of intensity-modulated
proton therapy (IMPT) to intensity-modulated radiation therapy (IMRT) in patients with locally …

Proton therapy for locally advanced non-small cell lung cancer

O Gjyshi, Z Liao - The British journal of radiology, 2020 - academic.oup.com
Radiation therapy is an essential component of treatment for locally advanced non-small cell
lung cancer (NSCLC) but can be technically challenging because of the proximity of lung …

Anatomical adaptation—early clinical evidence of benefit and future needs in lung cancer

J Kavanaugh, G Hugo, CG Robinson… - Seminars in radiation …, 2019 - Elsevier
Definitive treatment of locally advanced non–small-cell lung cancer with radiation is
challenging. During the course of treatment, anatomical changes such as tumor regression …