State of the field in multi-omics research: from computational needs to data mining and sharing

M Krassowski, V Das, SK Sahu, BB Misra - Frontiers in Genetics, 2020 - frontiersin.org
Multi-omics, variously called integrated omics, pan-omics, and trans-omics, aims to combine
two or more omics data sets to aid in data analysis, visualization and interpretation to …

Missing data in multi-omics integration: Recent advances through artificial intelligence

JE Flores, DM Claborne, ZD Weller… - Frontiers in Artificial …, 2023 - frontiersin.org
Biological systems function through complex interactions between various 'omics
(biomolecules), and a more complete understanding of these systems is only possible …

Circulating microRNA signatures associated with disease severity and outcome in COVID-19 patients

A Giannella, S Riccetti, A Sinigaglia, C Piubelli… - Frontiers in …, 2022 - frontiersin.org
Background SARS-CoV-2 induces a spectrum of clinical conditions ranging from
asymptomatic infection to life threatening severe disease. Host microRNAs have been …

Non-coding RNAs in human breast milk: A systematic review

L Tingö, E Ahlberg, L Johansson, SA Pedersen… - Frontiers in …, 2021 - frontiersin.org
Breast milk is the primary source of nutrition and hydration for the newborn infant but also
plays an important role in the child's first immune defense. Additionally, several breast milk …

Exploiting circulating MicroRNAs as biomarkers in psychiatric disorders

B Roy, Y Yoshino, L Allen, K Prall, G Schell… - Molecular diagnosis & …, 2020 - Springer
Non-invasive peripheral biomarkers play a significant role in both disease diagnosis and
progression. In the past few years, microRNA (miRNA) expression changes in circulating …

[HTML][HTML] A bioinformatics approach to microRNA-sequencing analysis

P Potla, SA Ali, M Kapoor - Osteoarthritis and cartilage open, 2021 - Elsevier
The rapid expansion of Next Generation Sequencing (NGS) data availability has made
exploration of appropriate bioinformatics analysis pipelines a timely issue. Since there are …

Development of circulating microRNA-based biomarkers for medical decision-making: a friendly reminder of what should NOT be done

P Lakkisto, LT Dalgaard, T Belmonte… - Critical Reviews in …, 2023 - Taylor & Francis
Circulating cell-free microRNAs (miRNAs) represent a major reservoir for biomarker
discovery. Unfortunately, their implementation in clinical practice is limited due to a profound …

Perspectives and challenges of epigenetic determinants of childhood obesity: a systematic review

R Alfano, O Robinson, E Handakas, TS Nawrot… - Obesity …, 2022 - Wiley Online Library
The tremendous increase in childhood obesity prevalence over the last few decades cannot
merely be explained by genetics and evolutionary changes in the genome, implying that …

Circulating microRNAs differentiate fast-progressing from slow-progressing and non-progressing knee osteoarthritis in the Osteoarthritis Initiative cohort

SA Ali, O Espin-Garcia, AK Wong… - Therapeutic …, 2022 - journals.sagepub.com
Introduction: The objective of this study is to identify circulating microRNAs that distinguish
fast-progressing radiographic knee osteoarthritis (OA) in the Osteoarthritis Initiative cohort by …

MiR-223-3p and miR-122-5p as circulating biomarkers for plaque instability

S Singh, MWJ de Ronde, MGM Kok, MAM Beijk… - Open …, 2020 - openheart.bmj.com
Background In this study, we discovered and validated candidate microRNA (miRNA)
biomarkers for coronary artery disease (CAD). Method Candidate tissue-derived miRNAs …