Significance: Albumin is the major contributor to colloid oncotic pressure and also serves as
an important carrier protein of many endogenous and exogenous molecules throughout the …

Reactive oxygen species (ROS) are implicated in inflammatory, autoimmune, and
neurodegenerative diseases. The activation, proliferation, and apoptosis of immune cells …

An emerging approach for multiplexed targeted proteomics involves bottom‐up LC‐MRM‐
MS, with stable isotope‐labeled internal standard peptides, to accurately quantitate panels …

Extending lifespan by lowering ambient temperature in the habitat has been shown in a
variety of organisms. Its mechanism, however, remains elusive. In this study, we examined …

Abstract Protein modifications by 4-hydroxy-2-nonenals (HNE) are involved in various
diseases. Histones are DNA protective nucleoprotein, which adopt different structures under …

Regulation of melanogenesis by tyrosinase has now become an attractive approach for
treatment of vitiligo but still the role of tyrosinase in the induction of depigmentation remains …

Objective Role of reactive oxygen species (ROS) modified human Immunoglobulin G (IgG)
in systemic lupus erythematosus (SLE) has been investigated. Methods Human IgG was …

Peroxynitrite (ONOO−) is a reactive oxidant involved in numerous pathological conditions.
Thymoquinone (TQ) is an active constituent of Nigella sativa and is reported to have anti …

Background Alopecia areata (AA) is a common form of localized, non-scarring hair loss. The
cause of AA is unknown but reports suggest an autoimmune etiology, where oxygen free …

Objective To investigate the status and contribution of oxidized superoxide dismutase (SOD)
in systemic lupus erythematosus (SLE), and to explore whether oxidized-SOD has a role in …