miRNAs can be found in serum and other body fluids and serve as biomarkers for disease.
More importantly, secreted miRNAs, especially those in extracellular vesicles (EVs) such as …

Extracellular vesicles (EVs) are submicron-sized lipid envelopes that are produced and
released from a parent cell and can be taken up by a recipient cell. EVs are capable of …

Type 2 diabetes is a chronic age-associated degenerative metabolic disease that reflects
relative insulin deficiency and resistance. Extracellular vesicles (EVs)(exosomes …

Purpose: In this study, we aim to investigate whether mesenchymal stem cell (MSC)-derived
exosomes (MSC-Exos) could regulate hyperglycemia-induced retinal inflammation by …

Cell-to-cell communication happens via diverse mechanisms including the synthesis,
release and transfer to target cells of extracellular vesicles (EVs). EVs include nanovesicles …

Microvesicles (MVs) circulating in the blood are small vesicles (100–1,000 nm in diameter)
derived from membrane blebs of cells such as activated platelets, endothelial cells, and …

Extracellular vesicles (EVs) including exosomes, microvesicles (MVs), and apoptotic bodies,
are small membrane vesicular structures that are released during cell activation …

The endothelial cell response to glucose plays an important role in both health and disease.
Endothelial glucose-induced dysfunction was first studied in diabetic animal models and in …

Metabolic syndrome defines a cluster of interrelated risk factors for cardiovascular disease
and diabetes mellitus. These factors include metabolic abnormalities, such as …

Abstract Significance: Secreted extracellular vesicles (EVs) are now considered veritable
entities for diagnosis, prognosis, and therapeutics. These structures are able to interact with …