Neutrophils have traditionally been viewed as bystanders or biomarkers of cardiovascular
disease. However, studies in the past decade have demonstrated the important functions of …

Improvements in early interventions after acute myocardial infarction (AMI), notably, the
increased use of timely reperfusion therapy, have increased survival dramatically in recent …

Myocardial infarction (MI), as a result of thrombosis or vascular occlusion, is the most
prevalent cause of morbidity and mortality among all cardiovascular diseases. The …

Macrophages are the most important phagocytes in vivo. However, the tumor
microenvironment can affect the function and polarization of macrophages and form tumor …

Inflammatory processes are firmly established as central to the development and
complications of cardiovascular diseases. Elevated levels of inflammatory markers have …

Macrophages play critical roles in homeostatic maintenance of the myocardium under
normal conditions and in tissue repair after injury. In the steady-state heart, resident cardiac …

Macrophages are ubiquitous cells that reside in all major tissues. Counter to long-held
beliefs, we now know that resident macrophages in many organs are seeded during …

Myocardial infarction is defined as sudden ischemic death of myocardial tissue. In the
clinical context, myocardial infarction is usually due to thrombotic occlusion of a coronary …

Macrophages are integral components of cardiac tissue and exert profound effects on the
healthy and diseased heart. Paradigm shifting studies using advanced molecular …

The mammalian heart contains a population of resident macrophages that expands in
response to myocardial infarction and hemodynamic stress. This expansion occurs likely …