Bioadhesive technology platforms

SJ Wu, X Zhao - Chemical Reviews, 2023 - ACS Publications
Bioadhesives have emerged as transformative and versatile tools in healthcare, offering the
ability to attach tissues with ease and minimal damage. These materials present numerous …

Chitosan-based hemostatic hydrogels: The concept, mechanism, application, and prospects

P Fan, Y Zeng, D Zaldivar-Silva, L Agüero, S Wang - Molecules, 2023 - mdpi.com
The design of new hemostatic materials to mitigate uncontrolled bleeding in emergencies is
challenging. Chitosan-based hemostatic hydrogels have frequently been used for …

Flexible bioactive glass nanofiber-based self-expanding cryogels with superelasticity and bioadhesion enabling hemostasis and wound healing

X Lu, Z Liu, Q Jia, Q Wang, Q Zhang, X Li, J Yu… - ACS nano, 2023 - ACS Publications
Self-expanding cryogels hold unique prospects for treating uncontrollable hemorrhages.
However, development of a mechanically robust, tissue-adhesive, and bioactive self …

Gelable and Adhesive Powder for Lethal Non‐Compressible Hemorrhage Control

K Zhang, Y Xian, M Li, Z Pan, Z Zhu… - Advanced Functional …, 2023 - Wiley Online Library
Hemostatic powders are widely used in clinical and emergency situations but often exhibit
low wet adhesion, cytotoxicity concerns, and do not work well for lethal non‐compressible …

A choline phosphoryl-conjugated chitosan/oxidized dextran injectable self-healing hydrogel for improved hemostatic efficacy

Z Zhu, K Zhang, Y Xian, G He, Z Pan, H Wang… - …, 2022 - ACS Publications
The development of injectable hydrogels with good biocompatibility, self-healing, and
superior hemostatic properties is highly desirable in emergency and clinical applications …

Mimosa‐Inspired Stimuli‐Responsive Curling Bioadhesive Tape Promotes Peripheral Nerve Regeneration

M Zhang, H An, Z Gu, Z Huang, F Zhang… - Advanced …, 2023 - Wiley Online Library
Trauma often results in peripheral nerve injuries (PNIs). These injuries are particularly
challenging therapeutically because of variable nerve diameters, slow axonal regeneration …

Dopamine‐Based High‐Transparent Hydrogel as Bioadhesive for Sutureless Ocular Tissue Repair

Y Qian, K Xu, L Shen, M Dai, Z Zhao… - Advanced Functional …, 2023 - Wiley Online Library
Ocular injuries and their complications represent the most common causes of visual
impairment. For ocular surgery, there is an unmet need for highly transparent bioadhesives …

Rational design of bioactive materials for bone hemostasis and defect repair

Y Gai, Y Yin, L Guan, S Zhang, J Chen… - Cyborg and Bionic …, 2023 - spj.science.org
Everyday unnatural events such as trauma, accidents, military conflict, disasters, and even
medical malpractice create open wounds and massive blood loss, which can be life …

Biomimetic and Multifunctional Hemostatic Hydrogel with Rapid Thermoresponsive Gelation and Robust Wet Adhesion for Emergency Hemostasis: A Rational Design …

H Song, L Xing, W Liu, X Wang, Z Hou… - …, 2023 - ACS Publications
Uncontrolled bleeding in emergency situations is a great threat to both military and civilian
lives, and an ideal hemostat for effectively controlling prehospital hemorrhage is urgently …

Quaternized chitosan/oxidized bacterial cellulose cryogels with shape recovery for noncompressible hemorrhage and wound healing

Y Li, C Chu, C Chen, B Sun, J Wu, S Wang, W Ding… - Carbohydrate …, 2024 - Elsevier
Management of noncompressible torso hemorrhage is an urgent clinical requirement,
desiring biomaterials with rapid hemostasis, anti-infection and excellent resilient properties …