Anagen stage hair follicles (HFs) exhibit “immune privilege (IP)” from the level of the bulge
downwards to the bulb. Both passive and active IP mechanisms protect HFs from …

The adaptive immune system and associated inflammation are vital in surveillance and host
protection against internal and external threats, but can secondarily damage host tissues …

The pathogenesis of periodontitis involves a complex immune/inflammatory cascade that is
initiated by the bacteria of the oral biofilm that forms naturally on the teeth. The susceptibility …

Complex barriers separate immune-privileged tissues from the circulation. Here, we propose
that cell entry to immune-privileged sites through barriers composed of tight junction …

Most higher animals require sight for survival, yet even minor distortions of the visual axis
can cause blindness. For this reason, intraocular inflammation is incompatible with good …

Corneal transplantation is the most successful solid organ transplantation performed in
humans. The extraordinary success of orthotopic corneal allografts, in both humans and …

Immune-mediated inflammation and allograft rejection are greatly reduced in certain organs,
a phenomenon called'immune privilege'. Immune privilege is well developed in three …

Allografts are afforded a level of protection from rejection within immune-privileged tissues.
Immune-privileged tissues involve mechanisms that suppress inflammation and promote …

It has been over 60 years since the phrase immune privilege was used by Sir Peter
Medawar to describe the lack of an immune response against allografts placed into the …

Immune privilege was first explored in the late 1800s by van Dooremaal, and was then
extended by Medawar in the mid 1900s to fit in with emerging concepts of transplantation …