Non-coding RNAs: the new central dogma of cancer biology
The central dogma of molecular biology states that the functions of RNA revolve around
protein translation. Until the last decade, most researches were geared towards …
protein translation. Until the last decade, most researches were geared towards …
Prognostic biomarkers of cell proliferation in colorectal cancer (CRC): from immunohistochemistry to molecular biology techniques
A Kasprzak - Cancers, 2023 - mdpi.com
Simple Summary This review aims to shed light on the proliferative markers important in the
everyday clinical management of colorectal cancer (CRC), ranging from simple methods of …
everyday clinical management of colorectal cancer (CRC), ranging from simple methods of …
Progress in genome-wide identification of RBPs and their role in mitigating stresses, and growth in plants
Recent ribonomics research has shed light on thousands of RNA Binding Proteins (RBPs)
that regulate post-transcriptional changes critical to plant development, growth, and …
that regulate post-transcriptional changes critical to plant development, growth, and …
Functional classification of plant long noncoding RNAs: a transcript is known by the company it keeps
The extraordinary maturation in high‐throughput sequencing technologies has revealed the
existence of a complex network of transcripts in eukaryotic organisms, including thousands …
existence of a complex network of transcripts in eukaryotic organisms, including thousands …
RNA structures in alternative splicing and back‐splicing
B Xu, Y Meng, Y Jin - Wiley Interdisciplinary Reviews: RNA, 2021 - Wiley Online Library
Alternative splicing greatly expands the transcriptomic and proteomic diversities related to
physiological and developmental processes in higher eukaryotes. Splicing of long …
physiological and developmental processes in higher eukaryotes. Splicing of long …
A novel MYCN-YTHDF1 cascade contributes to retinoblastoma tumor growth by eliciting m6A -dependent activation of multiple oncogenes
Y Luo, M He, J Yang, F Zhang, J Chen, X Wen… - Science China Life …, 2023 - Springer
Retinoblastoma, the most prevalent primary intraocular tumor in children, leads to vision
impairment, disability and even death. In addition to RB1 inactivation, MYCN activation has …
impairment, disability and even death. In addition to RB1 inactivation, MYCN activation has …
Noncoding RNA: from dark matter to bright star
The central dogma states that genes encoded in the DNA should be first transcribed into
messenger RNA (mRNA) and then translated into functional proteins (Crick, 1970). This …
messenger RNA (mRNA) and then translated into functional proteins (Crick, 1970). This …
Single-base resolution mapping of 2′-O-methylation sites by an exoribonuclease-enriched chemical method
P Zhang, J Huang, W Zheng, L Chen, S Liu… - Science China Life …, 2023 - Springer
O-methylation (Nm) is one of the most abundant RNA epigenetic modifications and plays a
vital role in the post-transcriptional regulation of gene expression. Current Nm mapping …
vital role in the post-transcriptional regulation of gene expression. Current Nm mapping …
Mass-Spectrometry-Based Assay at Single-Base Resolution for Simultaneously Detecting m6A and m6Am in RNA
Q Sun, H Li, Z Lin, G Cao, D Yang, D Tang… - Analytical …, 2024 - ACS Publications
The methylation modifications of adenosine, especially N 6-methyladenosine (m6A) and N
6, 2′-odimethyladenosine (m6Am), play vital roles in various biological, physiological, and …
6, 2′-odimethyladenosine (m6Am), play vital roles in various biological, physiological, and …
Recent advances in RNA structurome
B Xu, Y Zhu, C Cao, H Chen, Q Jin, G Li, J Ma… - Science China Life …, 2022 - Springer
RNA structures are essential to support RNA functions and regulation in various biological
processes. Recently, a range of novel technologies have been developed to decode …
processes. Recently, a range of novel technologies have been developed to decode …