Polysaccharide-based nanomedicines targeting lung cancer

AA Bhat, G Gupta, KS Alharbi, O Afzal, ASA Altamimi… - Pharmaceutics, 2022 - mdpi.com
A primary illness that accounts for a significant portion of fatalities worldwide is cancer.
Among the main malignancies, lung cancer is recognised as the most chronic kind of cancer …

Bioinspired and biomimetic micro-and nanostructures in biomedicine

AP Johnson, C Sabu, KP Nivitha, R Sankar… - Journal of Controlled …, 2022 - Elsevier
Bioinspired and biomimetic micro-and nanostructures have a high significance in the field of
biomedicine. In this review, the possible applications of these micro-and nanostructures that …

Targeted clindamycin delivery to pilosebaceous units by chitosan or hyaluronic acid nanoparticles for improved topical treatment of acne vulgaris

S Tolentino, MN Pereira, M Cunha-Filho, T Gratieri… - Carbohydrate …, 2021 - Elsevier
We developed chitosan or hyaluronic acid nanoparticles to entrap clindamycin and
evaluated for the first time the impact of these two polymeric nanosystems on the targeted …

The effect of electrostatic high pressure nebulization on the stability, activity and ex vivo distribution of ionic self-assembled nanomedicines

H Braet, V Andretto, R Mariën, B Yücesan… - Acta Biomaterialia, 2023 - Elsevier
Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is applied to treat unresectable
peritoneal metastasis (PM), an advanced, end-stage disease with a poor prognosis …

Hyaluronic acid: Its versatile use in ocular drug delivery with a specific focus on hyaluronic acid-based polyelectrolyte complexes

S Casey-Power, R Ryan, G Behl, P McLoughlin… - Pharmaceutics, 2022 - mdpi.com
Extensive research is currently being conducted into novel ocular drug delivery systems
(ODDS) that are capable of surpassing the limitations associated with conventional …

Extracellular matrix component-derived nanoparticles for drug delivery and tissue engineering

KJ Hogan, MR Perez, AG Mikos - Journal of Controlled Release, 2023 - Elsevier
The extracellular matrix (ECM) consists of a complex combination of proteins, proteoglycans,
and other biomolecules. ECM-based materials have been demonstrated to have high …

Nanoemulsions embedded in alginate beads as bioadhesive nanocomposites for intestinal delivery of the anti-inflammatory drug tofacitinib

V Andretto, G Taurino, G Guerriero, H Guérin… - …, 2023 - ACS Publications
Oral administration of nanoparticles (NPs) is a promising strategy to overcome solubility and
stability issues of many active compounds. However, this route faces major obstacles related …

N-acetyl-d-glucosamine-conjugated PAMAM dendrimers as dual receptor-targeting nanocarriers for anticancer drug delivery

D Pooja, TS Reddy, H Kulhari, A Kadari… - European Journal of …, 2020 - Elsevier
Abstract N-acetyl-d-glucosamine-labelled dendrimers (NAG-Dend) were synthesized for the
targeted delivery of camptothecin (CPT) to A549 human lung adenocarcinoma cells, which …

Hyaluronic acid-based nanomaterials applied to cancer: where are we now?

V Machado, M Morais, R Medeiros - Pharmaceutics, 2022 - mdpi.com
Cancer cells normally develop the ability to rewire or reprogram themselves to become
resistant to treatments that were previously effective. Despite progress in understanding …

Synergy between intraperitoneal aerosolization (PIPAC) and cancer nanomedicine: cisplatin-loaded polyarginine-hyaluronic acid nanocarriers efficiently eradicate …

M Shariati, G Lollo, K Matha, B Descamps… - … applied materials & …, 2020 - ACS Publications
Intra-abdominal dissemination of peritoneal nodules, a condition known as peritoneal
carcinomatosis (PC), is typically diagnosed in ovarian cancer patients at the advanced …