Post-discharge morbidity and mortality in children admitted with severe anaemia and other health conditions in malaria-endemic settings in Africa: a systematic review …

TK Kwambai, AT Mori, S Nevitt, AM van Eijk… - The Lancet Child & …, 2022 - thelancet.com
Background Severe anaemia is associated with high in-hospital mortality among young
children. In malaria-endemic areas, surviving children also remain at increased risk of …

[HTML][HTML] Pediatric post-discharge mortality in resource-poor countries: a systematic review and meta-analysis

M Knappett, V Nguyen, M Chaudhry, J Trawin… - …, 2024 - thelancet.com
Background Under-five mortality remains concentrated in resource-poor countries. Post-
discharge mortality is becoming increasingly recognized as a significant contributor to …

Ticagrelor vs placebo for the reduction of vaso-occlusive crises in pediatric sickle cell disease: the HESTIA3 study

MM Heeney, MR Abboud, J Githanga… - Blood, The Journal …, 2022 - ashpublications.org
The phase 3 HESTIA3 study assessed the efficacy and safety of the reversible P2Y12
inhibitor ticagrelor vs placebo in preventing vaso-occlusive crises in pediatric patients with …

Verbal autopsy to assess postdischarge mortality in children with suspected sepsis in Uganda

M Knappett, A Hooft, MB Maqsood, PM Lavoie… - …, 2023 - publications.aap.org
BACKGROUND Reducing child mortality in low-income countries is constrained by a lack of
vital statistics. In the absence of such data, verbal autopsies provide an acceptable method …

End points for sickle cell disease clinical trials: renal and cardiopulmonary, cure, and low-resource settings

AT Farrell, J Panepinto, AA Desai, AA Kassim… - Blood …, 2019 - ashpublications.org
To address the global burden of sickle cell disease and the need for novel therapies, the
American Society of Hematology partnered with the US Food and Drug Administration to …

[HTML][HTML] Challenges in pediatric post-sepsis care in resource limited settings: a narrative review

MO Wiens, N Kissoon, L Holsti - Translational Pediatrics, 2021 - ncbi.nlm.nih.gov
Objective The objective of this narrative review is to outline the current epidemiology and
interventional research within the context of sepsis recovery, and to provide a summary of …

Very severe anemia and one year mortality outcome after hospitalization in Tanzanian children: A prospective cohort study

N Chami, DK Hau, TS Masoza, LR Smart… - PloS one, 2019 - journals.plos.org
Background Africa has the highest rates of child mortality. Little is known about outcomes
after hospitalization for children with very severe anemia. Objective To determine one year …

Mortality during and following hospital admission among school-aged children: a cohort study

MM Ngari, C Obiero, MK Mwangome… - Wellcome open …, 2021 - pmc.ncbi.nlm.nih.gov
Background: Far less is known about the reasons for hospitalization or mortality during and
after hospitalization among school-aged children than among under-fives in low-and middle …

A study protocol for predictors of post-discharge mortality among children aged 5–14 years admitted to tertiary hospitals in Tanzania: A prospective observational …

ER Meleki, S Mongella, FF Furia - Plos one, 2024 - journals.plos.org
Introduction Globally, millions of children and adolescents die every year from treatable and
preventable causes. Sub-Saharan Africa accounted for 55% of deaths of children aged 5–14 …

Mortality after hospital discharge among children younger than 5 years admitted with suspected sepsis in Uganda: a prospective, multisite, observational cohort study

MO Wiens, JN Bone, E Kumbakumba… - The Lancet Child & …, 2023 - thelancet.com
Background Substantial mortality occurs after hospital discharge in children younger than 5
years with suspected sepsis, especially in low-income countries. A better understanding of …