This is a narrative review on the role of biomarkers in the diagnosis of neonatal sepsis. We
describe the difficulties to obtain standardized definitions in neonatal sepsis and discuss the …

Neonatal sepsis is a major cause of morbidity and mortality in both preterm and term infants.
Early-onset neonatal sepsis (EONS) presents within the first 72 h of life. Diagnosis is difficult …

Objective: This case-control study of chronic lung disease (CLD) evaluated the hypothesis
that chorioamnionitis promotes CLD and interacts with other risk factors for CLD, including …

Neonatal sepsis is a bacterial bloodstream infection leading to severe clinical manifestations
frequently associated with death or irreversible long-term deficits. Antibiotics are the drug of …

Perinatal brain damage has been implicated in the pathogenesis of neurodevelopmental
impairments and psychiatric illnesses. This article reviews evidence that infection outside of …

Background Neonatal infections annually claim lives of 1.4 million neonates worldwide. Until
now, there is no ideal diagnostic test for detecting sepsis and thus management of possible …

The inflammatory response plays a major role in the induction of several neonatal diseases.
We hypothesize that an imbalance between the pro-and anti-inflammatory response is …

OBJECTIVE: The amniotic cavity is normally sterile for bacteria. However, experimental
evidence indicates that regular uterine contractions exert a suction-like effect whereby …

It is now accepted that local changes to the balance of Th1/Th2-type cytokines occur during
pregnancy within the maternal uterus and fetoplacental unit. These changes in cytokine …

There is growing evidence that sepsis-related complications in neonates are crucially
mediated by the action of proinflammatory cytokines. It has previously been demonstrated …