Systems biology approaches for the improvement of oncolytic virus-based immunotherapies
L Tripodi, E Sasso, S Feola, L Coluccino, M Vitale… - Cancers, 2023 - mdpi.com
Simple Summary This review provides a roadmap to develop safe and effective OV-based
future therapeutics by using several novel synthetic and system biology strategies …
future therapeutics by using several novel synthetic and system biology strategies …
B3Pdb: an archive of blood–brain barrier-penetrating peptides
The blood–brain barrier poses major hurdles in the treatment of brain-related ailments. Over
the past decade, interest in peptides-based therapeutics has thrived a lot because of their …
the past decade, interest in peptides-based therapeutics has thrived a lot because of their …
Development of molecular mechanisms and their application on oncolytic Newcastle disease virus in cancer therapy
F Huang, C Dai, Y Zhang, Y Zhao, Y Wang… - Frontiers in Molecular …, 2022 - frontiersin.org
Cancer is caused by the destruction or mutation of cellular genetic materials induced by
environmental or genetic factors. It is defined by uncontrolled cell proliferation and …
environmental or genetic factors. It is defined by uncontrolled cell proliferation and …
Synthetic biology approaches for engineering next-generation adenoviral gene therapies
LT Collins, DT Curiel - ACS nano, 2021 - ACS Publications
Synthetic biology centers on the design and modular assembly of biological parts so as to
construct artificial biological systems. Over the past decade, synthetic biology has …
construct artificial biological systems. Over the past decade, synthetic biology has …
Progress in gene therapy treatments for prostate cancer
J Xue, K Chen, H Hu… - … and applied biochemistry, 2022 - Wiley Online Library
Prostate cancer is one of the predominant cancers affecting men and has been widely
reported. In the past, various therapies and drugs have been proposed to treat prostate …
reported. In the past, various therapies and drugs have been proposed to treat prostate …
Oncolytic Viruses in the Era of Omics, Computational Technologies, and Modeling: Thesis, Antithesis, and Synthesis
L Menotti, A Vannini - International Journal of Molecular Sciences, 2023 - mdpi.com
Oncolytic viruses (OVs) are the frontier therapy for refractory cancers, especially in
integration with immunomodulation strategies. In cancer immunovirotherapy, the many …
integration with immunomodulation strategies. In cancer immunovirotherapy, the many …
In-silico identification of subunit vaccine candidates against lung cancer-associated oncogenic viruses
Abstract Globally,~ 20% of cancer malignancies are associated with virus infections. Lung
cancer is the most prevalent cancer and has a 10% 5-year survival rate when diagnosed at …
cancer is the most prevalent cancer and has a 10% 5-year survival rate when diagnosed at …
DNA methylation, tumor microenvironment and their effects in immunotherapy and drug resistance in thoracic tumors
Thoracic tumors, such as lung cancer and breast cancer, are major contributors to cancer-
related fatalities, and their incidence is rapidly escalating (1). Currently, clinical treatments …
related fatalities, and their incidence is rapidly escalating (1). Currently, clinical treatments …
Identification of cancer types from gene expressions using learning techniques
Tumor is the major cause of death all around the world in recent days. Early detection and
prediction of a cancer type are important for a patient's well-being. Functional genomic data …
prediction of a cancer type are important for a patient's well-being. Functional genomic data …
Computational resources for identification of cancer biomarkers from omics data
Cancer is one of the most prevailing, deadly and challenging diseases worldwide. The
advancement in technology led to the generation of different types of omics data at each …
advancement in technology led to the generation of different types of omics data at each …