One of the most remarkable differences between classical engineering materials and living
matter is the ability of the latter to grow and remodel in response to diverse stimuli. The …

Pathological fibrosis is the result of a failure in the wound healing process. The
comprehension and the related modeling of the different mechanisms that trigger fibrosis are …

While cells within tissues generate and sense 3D states of strain, the current understanding
of the mechanics of fibrous extracellular matrices (ECMs) stems mainly from uniaxial, biaxial …

The development of soft tissue regeneration has recently gained importance due to safety
concerns about artificial breast implants. Current autologous fat graft implantations can …

The morphogenesis of tissues, like the deformation of an object, results from the interplay
between their material properties and the mechanical forces exerted on them. The …

A hallmark of biological cells is their ability to proliferate and of tissues their ability to grow.
This is common in morphogenesis and embryogenesis, but also in pathological conditions …

Polypropylene mesh is widely used in urogynecologic surgery, but complications rates (pain
and exposure) approach 10%. Emerging evidence implicates the adaptive immune system …

Several companies offer anatomically shaped breast implants but differences among
manufacturers are often misunderstood. The shell texture is a crucial parameter for …

Tissue engineering chamber technique can be used to generate engineered adipose tissue,
showing the potential for the reconstruction of soft tissue defects. However, the consequent …

For many organisms, shapes emerge from growth, which generates stresses, which in turn
can feedback on growth. In this review, theoretical methods to analyse various aspects of …