Microglia are the main resident immune cells of the nervous system and as such they are
involved in multiple roles ranging from tissue homeostasis to response to insults and circuit …

Microglia are increasingly shown to be key players in neuron development and synapse
connectivity. However, the underlying mechanisms by which microglia regulate neuron …

Background Microglia-driven cerebral spreading inflammation is a key contributor to
secondary brain injury after SAH. Genetic depletion or deactivation of microglia has been …

Microglia have important remodeling functions in neurodevelopment, aging, and disease,
with evidence for molecular diversity. However, the signaling pathways and environmental …

A highly efficient and regioselective direct C–H trifluoromethylation of pyridine based on an
N-methylpyridine quaternary ammonium activation strategy has been developed. A variety …

ABSTRACT A growing body of evidence highlights the importance of microglia, the resident
immune cells of the CNS, and their pro‐inflammatory activation in the onset of many …

Microglia, the resident immune cells of the central nervous system (CNS), were once
considered quiescent cells that sat in readiness for reacting to disease and injury. Over the …

Background Age-related macular degeneration (AMD) is the principal cause of permanent
blindness among elderly individuals worldwide. Chronic inflammation in the subretinal …

Microglia are known for important phagocytic functions in the vertebrate retina. Reports also
suggest that Müller glia have phagocytic capacity, though the relative levels and contexts in …

Background Prolonged exposure to general anesthetics during development is known to
cause neurobehavioral abnormalities, but the cellular and molecular mechanisms involved …