Parkinson's disease (PD) is a common neurodegenerative disorder. While a number of
nonmotor manifestations arise, the typical clinical features involve a movement disorder …

Parkinson's disease (PD) is a common motor disorder of mysterious etiology. It is due to the
progressive degeneration of the dopaminergic neurons of the substantia nigra and is …

Parkinson's disease (PD) is a progressive neurodegenerative movement disorder
associated with a selective loss of the dopamine (DA) rgic neurons in the substantia nigra …

Ubiquitin C-terminal hydrolase L1 (UCH-L1) is an extremely abundant protein in the brain
where, remarkably, it is estimated to make up 1–5% of total neuronal protein. Although it …

Alzheimer's disease (AD) and Parkinson's disease (PD) are the two most common
neurodegenerative diseases that occur either in relatively rare, familial forms or in common …

Parkinsonism is a progressive motor disease that affects 1.5 million Americans and is the
second most common neurodegenerative disease after Alzheimer's. Typical …

The elucidation of the function of the PINK1 protein kinase and Parkin ubiquitin E3 ligase in
the elimination of damaged mitochondria by autophagy (mitophagy) has provided …

A comprehensive focus on 4‐hydroxynonenal (HNE) as candidate molecule in a variety of
pathophysiological conditions occurring in humans is here provided. Despite an active, now …

Mutations in DJ-1 cause an autosomal recessive, early onset familial form of Parkinson
disease (PD). However, little is presently known about the role of DJ-1 in the more common …

The neuronal ubiquitin/proteasomal pathway has been implicated in the pathogenesis of
Alzheimer's disease (AD). We now show that a component of the pathway, ubiquitin C …