Circulating microRNAs in breast cancer: novel diagnostic and prognostic biomarkers

R Hamam, D Hamam, KA Alsaleh, M Kassem… - Cell death & …, 2017 - nature.com
Effective management of breast cancer depends on early diagnosis and proper monitoring
of patients' response to therapy. However, these goals are difficult to achieve because of the …

Exosome‐encapsulated microRNAs as circulating biomarkers for breast cancer

DP Joyce, MJ Kerin, RM Dwyer - International journal of cancer, 2016 - Wiley Online Library
Breast cancer is a highly prevalent disease, accounting for 29% of invasive cancers in
women. Survival from this disease depends on the stage at diagnosis, with patients who are …

Circulating microRNAs from the miR-106a–363 cluster on chromosome X as novel diagnostic biomarkers for breast cancer

M Li, Y Zhou, T Xia, X Zhou, Z Huang, H Zhang… - Breast cancer research …, 2018 - Springer
Purpose Novel noninvasive biomarkers with high sensitivity and specificity for the diagnosis
of breast cancer (BC) are urgently needed in clinics. The aim of this study was to explore …

HNRNPA2/B1 is upregulated in endocrine-resistant LCC9 breast cancer cells and alters the miRNA transcriptome when overexpressed in MCF-7 cells

CM Klinge, KM Piell, CS Tooley, EC Rouchka - Scientific reports, 2019 - nature.com
MicroRNAs are dysregulated in breast cancer. Heterogeneous Nuclear Ribonucleoprotein
A2/B1 (HNRNPA2/B1) is a reader of the N (6)-methyladenosine (m6A) mark in primary …

Emergence of circulating MicroRNAs in breast cancer as diagnostic and therapeutic efficacy biomarkers

V Aggarwal, K Priyanka, HS Tuli - Molecular diagnosis & therapy, 2020 - Springer
Breast cancer is the second most common cause of deaths reported in women worldwide,
and therefore there is a need to identify breast cancer patients at an early stage as timely …

Critical analysis of the potential for microRNA biomarkers in breast cancer management

CR Graveel, HM Calderone, JJ Westerhuis… - Breast cancer: targets …, 2015 - Taylor & Francis
Breast cancer is a complex and heterogeneous disease. Signaling by estrogen receptor
(ER), progesterone receptor (PR), and/or human EGF-like receptor 2 (HER2) is a main driver …

Clinical relevance of circulating, cell-free and exosomal microRNAs in plasma and serum of breast cancer patients

H Schwarzenbach - Oncology research and treatment, 2017 - karger.com
The expression of microRNAs (miRNAs) in a tissue-and development-specific manner has
indicated that they play an essential role in the maintenance of biological homeostasis. In …

[HTML][HTML] The diagnostic value of circulating microRNAs for middle-aged (40–60-year-old) coronary artery disease patients

ASM Sayed, K Xia, F Li, X Deng, U Salma, T Li, H Deng… - Clinics, 2015 - SciELO Brasil
OBJECTIVE: Circulating microRNAs have been recognized as promising biomarkers for
various diseases. The present study aimed to explore the potential roles of circulating miR …

Age-related microRNAs in older breast cancer patients: biomarker potential and evolution during adjuvant chemotherapy

B Dalmasso, S Hatse, B Brouwers, A Laenen, L Berben… - BMC cancer, 2018 - Springer
Background MicroRNAs (miRNAs) are important regulators of cellular function and have
been associated with both aging and cancer, but the impact of chemotherapy on age-related …

Circulating MicroRNAs in cancer

KP O'Brien, E Ramphul, L Howard… - … Profiling: Methods and …, 2017 - Springer
It is believed that microRNAs have potential as circulating biomarkers of disease; however,
successful clinical implementation remains a challenge. This chapter highlights broad …