Ischemia and reperfusion–elicited tissue injury contributes to morbidity and mortality in a wide range of pathologies, including myocardial infarction, ischemic stroke, acute kidney …
M de Lera Ruiz, YH Lim, J Zheng - Journal of medicinal chemistry, 2014 - ACS Publications
The adenosine A2A receptor is a G-protein-coupled receptor (GPCR) that has been extensively studied during the past few decades because it offers numerous possibilities for …
AE Iskandrian, TM Bateman, L Belardinelli… - Journal of Nuclear …, 2007 - Springer
Background Earlier phase 1 and 2 studies have shown that regadenoson has desirable features as a stress agent for myocardial perfusion imaging. Methods and Results This …
W Al Jaroudi, AE Iskandrian - Journal of the American College of …, 2009 - jacc.org
Vasodilator stress myocardial perfusion imaging (MPI) accounts for up to 50% of all stress MPI studies performed in the US In 2008, the Food and Drug Administration approved …
E Panther, S Corinti, M Idzko, Y Herouy… - Blood, The Journal …, 2003 - ashpublications.org
Dendritic cells (DCs) express functional purinergic type 1 receptors, but the effects of adenosine in these antigen-presenting cells have been only marginally investigated. Here …
Inflammation must be inhibited in order to treat, eg, sepsis or autoimmune diseases or must be selectively enhanced to improve, for example, immunotherapies of tumors or the …
RA Dvorak, RKJ Brown, JR Corbett - Radiographics, 2011 - pubs.rsna.org
Nuclear medicine has long played an important role in the noninvasive evaluation of known or suspected coronary artery disease. The development of single photon emission …
L Yan, JC Burbiel, A Maaß… - Expert opinion on …, 2003 - Taylor & Francis
Adenosine is a physiological nucleoside which acts as an autocoid and activates G protein- coupled membrane receptors, designated A1, A2A, A2B and A3. Adenosine plays an …