[HTML][HTML] Carbohydrate-based drugs launched during 2000− 2021

X Cao, X Du, H Jiao, Q An, R Chen, P Fang… - … Pharmaceutica Sinica B, 2022 - Elsevier
Carbohydrates are fundamental molecules involved in nearly all aspects of lives, such as
being involved in formating the genetic and energy materials, supporting the structure of …

Ischemia and reperfusion—from mechanism to translation

HK Eltzschig, T Eckle - Nature medicine, 2011 - nature.com
Ischemia and reperfusion–elicited tissue injury contributes to morbidity and mortality in a
wide range of pathologies, including myocardial infarction, ischemic stroke, acute kidney …

Adenosine A2A Receptor as a Drug Discovery Target

M de Lera Ruiz, YH Lim, J Zheng - Journal of medicinal chemistry, 2014 - ACS Publications
The adenosine A2A receptor is a G-protein-coupled receptor (GPCR) that has been
extensively studied during the past few decades because it offers numerous possibilities for …

Adenosine versus regadenoson comparative evaluation in myocardial perfusion imaging: results of the ADVANCE phase 3 multicenter international trial

AE Iskandrian, TM Bateman, L Belardinelli… - Journal of Nuclear …, 2007 - Springer
Background Earlier phase 1 and 2 studies have shown that regadenoson has desirable
features as a stress agent for myocardial perfusion imaging. Methods and Results This …

Regadenoson: a new myocardial stress agent

W Al Jaroudi, AE Iskandrian - Journal of the American College of …, 2009 - jacc.org
Vasodilator stress myocardial perfusion imaging (MPI) accounts for up to 50% of all stress
MPI studies performed in the US In 2008, the Food and Drug Administration approved …

Adenosine affects expression of membrane molecules, cytokine and chemokine release, and the T-cell stimulatory capacity of human dendritic cells

E Panther, S Corinti, M Idzko, Y Herouy… - Blood, The Journal …, 2003 - ashpublications.org
Dendritic cells (DCs) express functional purinergic type 1 receptors, but the effects of
adenosine in these antigen-presenting cells have been only marginally investigated. Here …

Use of the A2A adenosine receptor as a physiological immunosuppressor and to engineer inflammation in vivo

MV Sitkovsky - Biochemical pharmacology, 2003 - Elsevier
Inflammation must be inhibited in order to treat, eg, sepsis or autoimmune diseases or must
be selectively enhanced to improve, for example, immunotherapies of tumors or the …

Interpretation of SPECT/CT myocardial perfusion images: common artifacts and quality control techniques

RA Dvorak, RKJ Brown, JR Corbett - Radiographics, 2011 - pubs.rsna.org
Nuclear medicine has long played an important role in the noninvasive evaluation of known
or suspected coronary artery disease. The development of single photon emission …

Nitrogen-containing condensed cyclic compound having a pyrazolyl group as a substituent group and pharmaceutical composition thereof

I Yoshida, N Yoneda, Y Ohashi, S Suzuki… - US Patent …, 2006 - Google Patents
2003-10-23 Assigned to EISAI CO., LTD. reassignment EISAI CO., LTD. ASSIGNMENT OF
ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: KAMATA, JUNICHI …

Adenosine receptor agonists: from basic medicinal chemistry to clinical development

L Yan, JC Burbiel, A Maaß… - Expert opinion on …, 2003 - Taylor & Francis
Adenosine is a physiological nucleoside which acts as an autocoid and activates G protein-
coupled membrane receptors, designated A1, A2A, A2B and A3. Adenosine plays an …