Inflammatory myofibroblastic tumour: state of the art

L Gros, AP Dei Tos, RL Jones, A Digklia - Cancers, 2022 - mdpi.com
Simple Summary Among sarcomas, which are rare cancers, inflammatory myofibroblastic
tumors are extremely rare. Unlike other subtypes, this is a largely oncogene-driven …

Crizotinib in ALK+ inflammatory myofibroblastic tumors—Current experience and future perspectives

TM Theilen, J Soerensen, K Bochennek… - Pediatric Blood & …, 2018 - Wiley Online Library
Inflammatory myofibroblastic tumor (IMT) and its subtype epithelioid inflammatory
myofibroblastic sarcoma (EIMS) are rare soft‐tissue tumors. As about 50% of IMT and 100 …

An Oncogenic NTRK Fusion in a Patient with Soft-Tissue Sarcoma with Response to the Tropomyosin-Related Kinase Inhibitor LOXO-101

RC Doebele, LE Davis, A Vaishnavi, AT Le… - Cancer discovery, 2015 - AACR
Oncogenic TRK fusions induce cancer cell proliferation and engage critical cancer-related
downstream signaling pathways. These TRK fusions occur rarely, but in a diverse spectrum …

Inflammatory myofibroblastic tumor from molecular diagnostics to current treatment

P Chmiel, A Słowikowska, Ł Banaszek… - Oncology …, 2024 - pmc.ncbi.nlm.nih.gov
Inflammatory myofibroblastic tumor (IMT) is a rare neoplasm with intermediate malignancy
characterized by a propensity for recurrence but a low metastatic rate. Diagnostic challenges …

Clinical, pathologic, and molecular features of inflammatory myofibroblastic tumors in children and adolescents

A Pire, D Orbach, L Galmiche, D Berrebi… - Pediatric blood & …, 2022 - Wiley Online Library
Background Inflammatory myofibroblastic tumors (IMT) are rare, intermediate malignant
tumors harboring frequent somatic molecular rearrangements. The management of IMT has …

[HTML][HTML] Off-label use of crizotinib as a neoadjuvant treatment for a young patient when conventional chemotherapy gave no benefits in stage IIIA non-small cell lung …

D Dumont, P Dô, D Lerouge, G Planchard… - The American journal …, 2017 - ncbi.nlm.nih.gov
Objective: Unusual setting of medical care Background: The treatment of locally advanced
non-small cell lung cancer involves a combination of chemotherapy, surgery, and …

Epithelioid inflammatory myofibroblastic sarcoma: a case report and brief literature review

W Dou, Y Guan, T Liu, H Zheng, S Feng, Y Wu… - Frontiers in …, 2023 - frontiersin.org
Epithelioid inflammatory myofibroblastic sarcoma (EIMS) is a rare variant of the inflammatory
myofibroblastic tumor, characterized by more aggressive clinical course and nuclear …

[HTML][HTML] Clinical features, treatment strategies, and prognosis of epithelioid inflammatory myofibroblastic sarcoma in children: a multicenter experience

H Cheng, Y Lin, J Zhu, H Qin, W Yang… - Translational …, 2024 - ncbi.nlm.nih.gov
Background Inflammatory myofibroblastic tumors (IMTs) are a spectrum of tumors that range
in morphology and biological behavior from benign, intermediate, to apparently malignant …

[HTML][HTML] Locally advanced inflammatory myofibroblastic tumor treated with targeted therapy: a case report and literature review

C Durham, M Clemons, A Alias, K Konduri - Cureus, 2022 - ncbi.nlm.nih.gov
Inflammatory myofibroblastic tumors (IMTs) are known to be associated with anaplastic
lymphoma kinase (ALK) gene rearrangements. Other molecular alterations such as ROS …

Epithelioid inflammatory myofibroblastic sarcoma presenting as gastrointestinal bleed: case report and literature review

A Giannaki, D Doganis, P Giamarelou, A Konidari - JPGN reports, 2021 - journals.lww.com
Myofibroblastic tumor is a mesenchymal neoplasm composed of myofibroblastic spindle
cells with inflammatory infiltrate and considered to be of low-malignant potential tumor …