Clinical use of polygenic risk scores (PRS) will look very different to the more familiar
monogenic testing. Here we argue that despite these differences, most of the ethical, legal …

Background Commonly used estimated glomerular filtration rate (eGFR) equations include a
Black race modifier (BRM) that was incorporated during equation derivation. Race is a social …

Assessment in African populations suggest adjustment for ethnicity in estimated glomerular
filtration rate (eGFR) equations derived from African Americans lead to overestimation of …

Background Glomerular filtration rate (GFR) is a measure of the combined rate of filtration of
all functional nephrons in the kidney. Measurement of GFR is used in the clinic to detect …

Introducción: en la adultez mayor la insuficiencia renal crónica es un problema de salud
pública. Objetivo: establecer la posible relación entre la progresión de la insuficiencia renal …

Abstract Background Sub-Saharan Africans exhibit a higher frequency of chronic kidney
disease (CKD) than other populations. In this study, we sought to determine the frequency of …

Background To determine the prevalence, distribution, concordance and associations of
chronic kidney disease (CKD) determined by five glomerular filtration rate (GFR) formulae in …

The widely used Modification of Diet in Renal Disease (MDRD) formula adapts a 1.212
multiplier for individuals who are identified as African Americans (AAs) or Blacks, which …

Creatinine-based estimated glomerular filtration rate equations (eGFRcreatinine) are used
to measure excretory kidney function in clinical practice. Despite inter and intra-patient …

In liver allocation systems based on the Model for End-stage Liver Disease (MELD) score,
sex inequities have been identified in countries with high organ donation rates. Whether …