Polyoxometalate nanomaterials for enhanced reactive oxygen species theranostics

J Liu, M Huang, X Zhang, Z Hua, Z Feng, Y Dong… - Coordination Chemistry …, 2022 - Elsevier
The dual effects of reactive oxygen species (ROS) on living organisms have become a hot
research topic in the biomedical field. Excessive ROS triggers oxidative imbalances in the …

Recent progress, perspectives, and issues of engineered PD-L1 regulation nano-system to better cure tumor: A review

Z Zhou, H Wang, J Li, X Jiang, Z Li, J Shen - International Journal of …, 2024 - Elsevier
Currently, immune checkpoint blockade (ICB) therapies that target the programmed cell
death ligand-1 (PD-L1) have been used as revolutionary cancer treatments in the clinic …

Mild near-infrared laser-triggered photo-immunotherapy potentiates immune checkpoint blockade via an all-in-one theranostic nanoplatform

Y Fan, R Zhang, J Shi, F Tian, Y Zhang, L Zhang… - Journal of Colloid and …, 2025 - Elsevier
One of the primary challenges for immune checkpoint blockade (ICB)-based therapy is the
limited infiltration of T lymphocytes (T cells) into tumors, often referred to as immunologically …

Nanoparticles mediated tumor microenvironment modulation: current advances and applications

GSR Raju, E Pavitra, GL Varaprasad… - Journal of …, 2022 - Springer
The tumor microenvironment (TME) plays a key role in cancer development and emergence
of drug resistance. TME modulation has recently garnered attention as a potential approach …

Antioxidant biodegradable covalent cyclodextrin frameworks as particulate carriers for inhalation therapy against acute lung injury

S He, L Wu, H Sun, D Wu, C Wang, X Ren… - … Applied Materials & …, 2022 - ACS Publications
Drug therapies for acute lung injury (ALI) are far from satisfactory, primarily because drugs
cannot specifically target the lungs. Direct delivery of drugs to the deep alveolar regions by …

Enhancement of blood–brain barrier penetration and the neuroprotective effect of resveratrol

N Katila, R Duwa, S Bhurtel, S Khanal… - Journal of Controlled …, 2022 - Elsevier
Parkinson's disease (PD) is a debilitating neurodegenerative condition characterized by the
loss of dopaminergic neurons within the substantia nigra. The specific molecular …

Tumor microenvironment and nanotherapeutics: intruding the tumor fort

AVVVR Kiran, GK Kumari, PT Krishnamurthy… - Biomaterials …, 2021 - pubs.rsc.org
Over recent years, advancements in nanomedicine have allowed new approaches to
diagnose and treat tumors. Nano drug delivery systems exploit the enhanced permeability …

Recent progress in stimuli-responsive nanosystems for inducing immunogenic cell death

A Banstola, K Poudel, JO Kim, JH Jeong… - Journal of Controlled …, 2021 - Elsevier
Low immunogenicity and immunosuppressive tumor microenvironments are major hurdles
in the application of cancer immunotherapy. To date, several immunogenic cell death (ICD) …

Inflammation-sensing catalase-mimicking nanozymes alleviate acute kidney injury via reversing local oxidative stress

HS Choi, AP Mathew, S Uthaman, A Vasukutty… - Journal of …, 2022 - Springer
Background The reactive oxygen species (ROS) and inflammation, a critical contributor to
tissue damage, is well-known to be associated with various disease. The kidney is …

Intelligent delivery system targeting PD-1/PD-L1 pathway for cancer immunotherapy

N Liu, R Zhang, Q Shi, H Jiang, Q Zhou - Bioorganic Chemistry, 2023 - Elsevier
The drugs targeting the PD-1/PD-L1 pathway have gained abundant clinical applications for
cancer immunotherapy. However, only a part of patients benefit from such immunotherapy …