Chagas disease: recombinant Trypanosoma cruzi antigens for serological diagnosis

JF Da Silveira, ES Umezawa, AO Luquetti - Trends in parasitology, 2001 - cell.com
Diagnosis of individuals infected by Trypanosoma cruzi is performed mainly by serological
tests using crude antigens, which might crossreact with other infections. In the past ten …

Safety of the blood supply in Latin America

GA Schmunis, JR Cruz - Clinical Microbiology Reviews, 2005 - Am Soc Microbiol
Appropriate selection of donors, use of sensitive screening tests, and the application of a
mandatory quality assurance system are essential to maintain the safety of the blood supply …

Ten-Year Incidence of Chagas Cardiomyopathy Among Asymptomatic Trypanosoma cruzi–Seropositive Former Blood Donors

EC Sabino, AL Ribeiro, VMC Salemi… - Circulation, 2013 - Am Heart Assoc
Background—Very few studies have measured disease penetrance and prognostic factors
of Chagas cardiomyopathy among asymptomatic Trypanosoma cruzi–infected persons …

Evaluation of Serological Tests To Identify Trypanosoma cruzi Infection in Humans and Determine Cross-Reactivity with Trypanosoma rangeli and Leishmania spp

ZC Caballero, OE Sousa, WP Marques… - Clinical and vaccine …, 2007 - Am Soc Microbiol
Five commercially available enzyme-linked immunosorbent assays (ELISAs), one in-house
ELISA, and two hemagglutination assays were evaluated to determine their diagnostic …

Emerging and reemerging forms of Trypanosoma cruzi transmission

MA Shikanai Yasuda - Memórias do Instituto Oswaldo Cruz, 2022 - SciELO Brasil
This review aims to update and discuss the main challenges in controlling emergent and
reemergent forms of Trypanosoma cruzi transmission through organ transplantation, blood …

WHO comparative evaluation of serologic assays for Chagas disease

MM Otani, E Vinelli, LV Kirchhoff, A Del Pozo… - …, 2009 - Wiley Online Library
BACKGROUND: Evaluation of commercially available test kits for Chagas disease for use in
blood bank screening is difficult due to a lack of large and well‐characterized specimen …

[PDF][PDF] Chagas' disease diagnosis: comparative analysis of parasitologic, molecular, and serologic methods.

ML Gomes, LM Galvao, AM Macedo… - The American journal …, 1999 - academia.edu
During the course of chronic chagasic infection, low parasitemia levels prevent parasite
detection by current techniques such as hemoculture and xenodiagnosis. Since serologic …

An improved serodiagnostic test for Chagas' disease employing a mixture of Trypanosoma cruzi recombinant antigens

ES Umezawa, SF Bastos, JR Coura, MJ Levin… - …, 2003 - Wiley Online Library
BACKGROUND: Blood transfusion is one of the most important transmission routes of
Chagas' disease, a major parasitic infection in Latin America. Therefore, screening for …

Chagas' heart disease

JA Marin-Neto, MV Simões… - Arquivos brasileiros de …, 1999 - SciELO Brasil
State of the Art tations and mortality due to Chagas' heart disease. However, no clear-cut
epidemiological picture of Chagas' heart disease is yet available, due to the lack of …

Cardiac involvement in Chagas disease and African trypanosomiasis

EC Sabino, MCP Nunes, J Blum, I Molina… - Nature Reviews …, 2024 - nature.com
Trypanosomiases are diseases caused by various species of protozoan parasite in the
genus Trypanosoma, each presenting with distinct clinical manifestations and prognoses …