First achieved in 1998 by Cole et al., the complete genome sequence of Mycobacterium
tuberculosis continues to provide an invaluable resource to understand tuberculosis (TB) …

Infectious diseases are a major threat to global health and cause millions of deaths every
year, particularly in developing countries. The emergence of multidrug resistance …

Host cytosolic sensing of Mycobacterium tuberculosis (M. tuberculosis) RNA by the RIG-I–
like receptor (RLR) family perturbs innate immune control within macrophages; however, a …

Mycobacterium tuberculosis (Mtb) strains are classified into different phylogenetic lineages
(L), three of which (L2/L3/L4) emerged from a common progenitor after the loss of the …

Mycobacterium tuberculosis (Mtb) is known to evade host immune responses and persist in
macrophages for long periods. A mechanism that the host uses to combat Mtb is xenophagy …

Genetic diversity of Mycobacterium tuberculosis affects immune responses and clinical
outcomes of tuberculosis (TB). However, how bacterial diversity orchestrates immune …

COVID-19 is currently a highly pressing health threat and therapeutic strategies to mitigate
the infection impact are urgently needed. Characterization of the SARS-CoV-2 interactome …

Periodontitis is highly prevalent worldwide. It is characterized by periodontal attachment and
alveolar bone destruction, which not only leads to tooth loss but also results in the …

Bacillus Calmette–Guérin (BCG) immunotherapy for bladder cancer has been used since
1976 when the first evidence of its ability to lower recurrence and progression rates was …

ABSTRACT Interleukin-1 (IL-1) is a key player in the immune response to pathogens due to
its role in promoting inflammation and recruiting immune cells to the site of infection. In …