Simple Summary DLX homeobox family genes encode transcription factors that have
indispensable roles in embryonic and postnatal development. These genes are critically …

Mild hyperthermia is greatly beneficial to the healing of bone defects; however, how to
generat hyperthermia directly at the bone defect site remains an unsolved problem due to …

Electrical stimulation can effectively accelerate bone healing. However, the substantial size
and weight of electrical stimulation devices result in reduced patient benefits and …

The residual bone tumor and defects which is caused by surgical therapy of bone tumor is a
major and important problem in clinicals. And the sequential treatment for irradiating …

Background It is reported that the osteogenesis in bone marrow mesenchymal stem cells
(BMSCs) can alleviate osteoporosis progression. It has been found that Kae can promote …

Titanium and its alloys are the most commonly used biometals for developing orthopedic
implants to treat various forms of bone fractures and defects, but their clinical performance is …

Osteogenic differentiation (OD) of bone marrow mesenchymal stem cells (BMSCs)
contributes significantly to the regeneration of bone defects. Resistin, an adipose tissue …

Abstract Intracellular phosphoinositide 3-kinase (PI3K) signaling is activated by multiple
bone-active receptors. Genetic mutations activating PI3K signaling are associated with …

The development of growth factor-free biomaterials for bone tissue regeneration with anti-
infection and anti-inflammatory activities remains challenging. Black phosphorus …

Recent studies have shown that the differentiation of bone marrow mesenchymal stem cells
(BMSCs) into osteogenic lineages can promotes bone formation and maintains bone …