Type II bacterial toxin–antitoxins: hypotheses, facts, and the newfound plethora of the PezAT system
Toxin–antitoxin (TA) systems are entities found in the prokaryotic genomes, with eight
reported types. Type II, the best characterized, is comprised of two genes organized as an …
reported types. Type II, the best characterized, is comprised of two genes organized as an …
Synthetic genetic oscillators demonstrate the functional importance of phenotypic variation in pneumococcal-host interactions
AS Rueff, R Van Raaphorst, SD Aggarwal… - Nature …, 2023 - nature.com
Phenotypic variation is the phenomenon in which clonal cells display different traits even
under identical environmental conditions. This plasticity is thought to be important for …
under identical environmental conditions. This plasticity is thought to be important for …
Non-invasive Streptococcus pneumoniae infections are associated with different serotypes than invasive infections, Belgium, 2020 to 2023
I Passaris, S Depickère, T Braeye… - …, 2024 - eurosurveillance.org
Background Despite widely implemented pneumococcal vaccination programmes,
Streptococcus pneumoniae remains a global risk for human health. Streptococcus …
Streptococcus pneumoniae remains a global risk for human health. Streptococcus …
Environmental and genetic regulation of Streptococcus pneumoniae galactose catabolic pathways
BO Kareem, O Gazioglu, K Mueller Brown… - Nature …, 2024 - nature.com
Efficient utilization of nutrients is crucial for microbial survival and virulence. The same
nutrient may be utilized by multiple catabolic pathways, indicating that the physical and …
nutrient may be utilized by multiple catabolic pathways, indicating that the physical and …
[HTML][HTML] A narrative review of genomic characteristics, serotype, immunogenicity, and vaccine development of Streptococcus pneumoniae capsular polysaccharide
This narrative review describes genomic characteristic, serotyping, immunogenicity, and
vaccine development of Streptococcus pneumoniae capsular polysaccharide (CPS). CPS is …
vaccine development of Streptococcus pneumoniae capsular polysaccharide (CPS). CPS is …
Point mutations in functionally diverse genes are associated with increased natural DNA transformation in multidrug resistant Streptococcus pneumoniae
F Peillard-Fiorente, NP Pham, H Gingras… - Nucleic Acids …, 2025 - academic.oup.com
DNA transformation is key for phenotypic diversity and adaptation of Streptococcus
pneumoniae including in the emergence of multidrug resistance (MDR). Under laboratory …
pneumoniae including in the emergence of multidrug resistance (MDR). Under laboratory …
Peptide maturation molecules act as molecular gatekeepers to coordinate cell-cell communication in Streptococcus pneumoniae
KM Brown, R Eutsey, O Gazioglu, D Wang, A Vallon… - Cell reports, 2024 - cell.com
The human pathogen Streptococcus pneumoniae (Spn) encodes several cell-cell
communication systems, notably multiple members of the Rgg/SHP and the Tpr/Phr families …
communication systems, notably multiple members of the Rgg/SHP and the Tpr/Phr families …
A TrmBL2-like transcription factor mediates the growth phase-dependent expression of halolysin SptA in a concentration-dependent manner in Natrinema gari J7-2
J Yin, Y Liu, D He, P Li, M Qiao, H Luo… - Applied and …, 2024 - journals.asm.org
To cope with a high-salinity environment, haloarchaea generally employ the twin-arginine
translocation (Tat) pathway to transport secretory proteins across the cytoplasm membrane …
translocation (Tat) pathway to transport secretory proteins across the cytoplasm membrane …
Expansion of pneumococcal serotype 23F and 14 lineages with genotypic changes in capsule polysaccharide locus and virulence gene profiles post introduction of …
Since the introduction of the 13-valent pneumococcal conjugate vaccine (PCV13) in Malawi
in 2011, there has been persistent carriage of vaccine serotype (VT) Streptococcus …
in 2011, there has been persistent carriage of vaccine serotype (VT) Streptococcus …
Increased Proportions of Invasive Pneumococcal Disease Cases Among Adults Experiencing Homelessness Sets the Stage for New Serotype 4 Capsular-Switch …
Abstract Background The Centers for Disease Control and Prevention's Active Bacterial
Core surveillance (ABCs) identified increased serotype 4 invasive pneumococcal disease …
Core surveillance (ABCs) identified increased serotype 4 invasive pneumococcal disease …