Collagen mimetic peptides (CMPs) fold into a polyproline type II triple helix, allowing the
study of the structure and function (or misfunction) of the collagen family of proteins. This …

In the growing field of tissue engineering, providing cells in biomaterials with the adequate
biological cues represents an increasingly important challenge. Yet, biomaterials with …

The folding of collagen is a hierarchical process that starts with three peptides associating
into the characteristic triple helical fold. Depending on the specific collagen in question …

Collagen is one of the most important structural proteins in biology, and its structural
hierarchy plays a crucial role in many mechanically important biomaterials. Here, we …

Collagen model peptides (CMPs) consisting of proline‐(2S, 4R)‐hydroxyproline‐glycine
(POG) repeats have provided a breadth of knowledge of the triple helical structure of …

Nature uses elaborate methods to control protein assembly, including that of heterotrimeric
collagen. Here, we established design principles for the composition and register-selective …

Under diabetic conditions, blood glucose fluctuations and exacerbated immunopathological
inflammatory environments pose significant challenges to periosteal regenerative repair …

Cation− π interactions play a significant role in the stabilization of globular proteins.
However, their role in collagen triple helices is less well understood and they have rarely …

Collagen made a tremendous impact in the field of regenerative medicine as a bioactive
material. For decades, collagen has been used not only as a scaffolding material but also as …

Collagen mimetic peptides (CMPs) are an excellent model to study the structural and
biological properties of the extracellular matrix (ECM) due to ease of synthesis and …