Genome stability is a crucial feature of eukaryotic organisms because its alteration
drastically affects the normal development and survival of cells and the organism as a …

Genetic information typically remains constant in all cells throughout the life cycle of most
organisms. However, there are exceptions where DNA elimination is an integral …

In some eukaryotes, germline and somatic genomes differ dramatically in their composition.
Here we characterise a major germline–soma dissimilarity caused by a germline-restricted …

The ability to generate haploids and subsequently induce chromosome doubling
significantly accelerates the crop breeding process. Haploids have been induced through …

Over the last few decades, an increasing number of vertebrate taxa have been identified that
undergo programmed genome rearrangement, or programmed DNA loss, during …

Chromatin diminution is the programmed elimination of specific DNA sequences during
development. It occurs in diverse species, but the function (s) of diminution and the …

DNA methylation (5mC) is a repressive gene regulatory mark widespread in vertebrate
genomes, yet the developmental dynamics in which 5mC patterns are established vary …

The ability to reproduce is the key trait that distinguishes living organisms from inorganic
matter, and the strategies used to achieve successful reproduction are almost as diverse as …

Germline-restricted chromosomes (GRCs) are accessory chromosomes that occur only in
germ cells. They are eliminated from somatic cells through programmed DNA elimination …

Developmentally programmed genome rearrangement accompanies differentiation of the
silent germline micronucleus into the transcriptionally active somatic macronucleus in the …