Septins: the fourth component of the cytoskeleton
S Mostowy, P Cossart - Nature reviews Molecular cell biology, 2012 - nature.com
Septins belong to a family of proteins that is highly conserved in eukaryotes and is
increasingly recognized as a novel component of the cytoskeleton. All septins are GTP …
increasingly recognized as a novel component of the cytoskeleton. All septins are GTP …
Cellular functions of actin-and microtubule-associated septins
ET Spiliotis, K Nakos - Current Biology, 2021 - cell.com
Septins are an integral component of the cytoskeleton, assembling into higher-order
oligomers and filamentous polymers that associate with actin filaments, microtubules and …
oligomers and filamentous polymers that associate with actin filaments, microtubules and …
Microglial-derived C1q integrates into neuronal ribonucleoprotein complexes and impacts protein homeostasis in the aging brain
Neuroimmune interactions mediate intercellular communication and underlie critical brain
functions. Microglia, CNS-resident macrophages, modulate the brain through direct physical …
functions. Microglia, CNS-resident macrophages, modulate the brain through direct physical …
C9orf72 FTLD/ALS-associated Gly-Ala dipeptide repeat proteins cause neuronal toxicity and Unc119 sequestration
S May, D Hornburg, MH Schludi, T Arzberger… - Acta …, 2014 - Springer
Hexanucleotide repeat expansion in C9orf72 is the most common pathogenic mutation in
patients with amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration …
patients with amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration …
ALS‐associated fused in sarcoma (FUS) mutations disrupt Transportin‐mediated nuclear import
D Dormann, R Rodde, D Edbauer, E Bentmann… - The EMBO …, 2010 - embopress.org
Mutations in fused in sarcoma (FUS) are a cause of familial amyotrophic lateral sclerosis
(fALS). Patients carrying point mutations in the C‐terminus of FUS show neuronal …
(fALS). Patients carrying point mutations in the C‐terminus of FUS show neuronal …
Actin in dendritic spines: connecting dynamics to function
P Hotulainen, CC Hoogenraad - Journal of Cell Biology, 2010 - rupress.org
Dendritic spines are small actin-rich protrusions from neuronal dendrites that form the
postsynaptic part of most excitatory synapses and are major sites of information processing …
postsynaptic part of most excitatory synapses and are major sites of information processing …
[HTML][HTML] Regulation of synaptic structure and function by FMRP-associated microRNAs miR-125b and miR-132
D Edbauer, JR Neilson, KA Foster, CF Wang… - Neuron, 2010 - cell.com
MicroRNAs (miRNAs) are noncoding RNAs that suppress translation of specific mRNAs. The
miRNA machinery interacts with fragile X mental retardation protein (FMRP), which functions …
miRNA machinery interacts with fragile X mental retardation protein (FMRP), which functions …
Dynamic organizing principles of the plasma membrane that regulate signal transduction: commemorating the fortieth anniversary of Singer and Nicolson's fluid …
A Kusumi, TK Fujiwara, R Chadda, M Xie… - Annual review of cell …, 2012 - annualreviews.org
The recent rapid accumulation of knowledge on the dynamics and structure of the plasma
membrane has prompted major modifications of the textbook fluid-mosaic model. However …
membrane has prompted major modifications of the textbook fluid-mosaic model. However …
A futile battle? Protein quality control and the stress of aging
There exists a phenomenon in aging research whereby early life stress can have positive
impacts on longevity. The mechanisms underlying these observations suggest a robust, long …
impacts on longevity. The mechanisms underlying these observations suggest a robust, long …