Senescence in the wild: Insights from a long-term study on Seychelles warblers

M Hammers, SA Kingma, K Bebbington… - Experimental …, 2015 - Elsevier
Senescence–the progressive age-dependent decline in performance–occurs in most
organisms. There is considerable variation in the onset and rate of senescence between …

Conservation genetics of population bottlenecks: the role of chance, selection, and history

JL Bouzat - Conservation Genetics, 2010 - Springer
Conservation genetics studies of populations bottlenecks are commonly framed under the
detrimental paradigm of inbreeding depression. This conceptual paradigm presupposes a …

The causes and consequences of inbreeding avoidance and tolerance in cooperatively breeding vertebrates

HJ Nichols - Journal of Zoology, 2017 - Wiley Online Library
Cooperative breeders provide a particularly interesting scenario for studying inbreeding.
Such populations are viscous due to delayed dispersal and short dispersal distances …

genhet: an easy‐to‐use R function to estimate individual heterozygosity

A Coulon - Molecular Ecology Resources, 2010 - Wiley Online Library
Abstract genhet is an R function which calculates the five most used estimates of individual
heterozygosity. The advantage of this program is that it can be applied to any diploid …

MHC‐dependent survival in a wild population: Evidence for hidden genetic benefits gained through extra‐pair fertilizations

L Brouwer, I Barr, M Van De POL, T Burke… - Molecular …, 2010 - Wiley Online Library
Females should prefer to be fertilized by males that increase the genetic quality of their
offspring. In vertebrates, genes of the major histocompatibility complex (MHC) play a key …

Immunogenetic variation shapes the gut microbiome in a natural vertebrate population

CS Davies, SF Worsley, KH Maher, J Komdeur, T Burke… - Microbiome, 2022 - Springer
Background The gut microbiome (GM) can influence many biological processes in the host,
impacting its health and survival, but the GM can also be influenced by the host's traits. In …

MHC heterozygosity and survival in red junglefowl

K Worley, J Collet, LG Spurgin, C Cornwallis… - Molecular …, 2010 - Wiley Online Library
Genes of the major histocompatibility complex (MHC) form a vital part of the vertebrate
immune system and play a major role in pathogen resistance. The extremely high levels of …

Telomere length reveals cumulative individual and transgenerational inbreeding effects in a passerine bird

K Bebbington, LG Spurgin, EA Fairfield… - Molecular …, 2016 - Wiley Online Library
Inbreeding results in more homozygous offspring that should suffer reduced fitness, but it
can be difficult to quantify these costs for several reasons. First, inbreeding depression may …

Heterozygosity–fitness correlations and their relevance to studies on inbreeding depression in threatened species

CE Grueber, GP Wallis, IG Jamieson - Molecular Ecology, 2008 - Wiley Online Library
The majority of reported multilocus heterozygosity–fitness correlations (HFCs) are from
large, outbred populations, and their relevance to studies on inbreeding depression in …

Contemporary evolution of the innate immune receptor gene TLR3 in an isolated vertebrate population

CS Davies, MI Taylor, M Hammers, T Burke… - Molecular …, 2021 - Wiley Online Library
Understanding where genetic variation exists, and how it influences fitness within
populations is important from an evolutionary and conservation perspective. Signatures of …