Signaling Cascades Governing Entry into and Exit from Host Cells by Toxoplasma gondii
H Bisio, D Soldati-Favre - Annual review of microbiology, 2019 - annualreviews.org
The Apicomplexa phylum includes a large group of obligate intracellular protozoan
parasites responsible for important diseases in humans and animals. Toxoplasma gondii is …
parasites responsible for important diseases in humans and animals. Toxoplasma gondii is …
[HTML][HTML] Calcium signaling and the lytic cycle of the Apicomplexan parasite Toxoplasma gondii
MAH Triana, KM Márquez-Nogueras, SA Vella… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Toxoplasma gondii has a complex life cycle involving different hosts and is dependent on
fast responses, as the parasite reacts to changing environmental conditions. T. gondii …
fast responses, as the parasite reacts to changing environmental conditions. T. gondii …
Phosphatidic acid-mediated signaling regulates microneme secretion in Toxoplasma
The obligate intracellular lifestyle of apicomplexan parasites necessitates an invasive phase
underpinned by timely and spatially controlled secretion of apical organelles termed …
underpinned by timely and spatially controlled secretion of apical organelles termed …
Depletion of a Toxoplasma porin leads to defects in mitochondrial morphology and contacts with the endoplasmic reticulum
N Mallo, J Ovciarikova… - Journal of Cell …, 2021 - journals.biologists.com
The voltage-dependent anion channel (VDAC) is a ubiquitous channel in the outer
membrane of the mitochondrion with multiple roles in protein, metabolite and small molecule …
membrane of the mitochondrion with multiple roles in protein, metabolite and small molecule …
Analysis of CDPK1 targets identifies a trafficking adaptor complex that regulates microneme exocytosis in Toxoplasma
Apicomplexan parasites use Ca 2+-regulated exocytosis to secrete essential virulence
factors from specialized organelles called micronemes. Ca 2+-dependent protein kinases …
factors from specialized organelles called micronemes. Ca 2+-dependent protein kinases …
An apical protein, Pcr2, is required for persistent movement by the human parasite Toxoplasma gondii
The phylum Apicomplexa includes thousands of species of unicellular parasites that cause a
wide range of human and animal diseases such as malaria and toxoplasmosis. To infect, the …
wide range of human and animal diseases such as malaria and toxoplasmosis. To infect, the …
Serum albumin stimulates protein kinase G-dependent microneme secretion in Toxoplasma gondii
Microneme secretion is essential for motility, invasion, and egress in apicomplexan
parasites. Although previous studies indicate that Ca 2+ and cGMP control microneme …
parasites. Although previous studies indicate that Ca 2+ and cGMP control microneme …
Protein kinase A negatively regulates Ca2+ signalling in Toxoplasma gondii
AD Uboldi, ML Wilde, EA McRae, RJ Stewart… - PLoS …, 2018 - journals.plos.org
The phylum Apicomplexa comprises a group of obligate intracellular parasites that alternate
between intracellular replicating stages and actively motile extracellular forms that move …
between intracellular replicating stages and actively motile extracellular forms that move …
Using a genetically encoded sensor to identify inhibitors of Toxoplasma gondii Ca2+ signaling
The life cycles of apicomplexan parasites progress in accordance with fluxes in cytosolic Ca
2+. Such fluxes are necessary for events like motility and egress from host cells. We used …
2+. Such fluxes are necessary for events like motility and egress from host cells. We used …
The triumvirate of signaling molecules controlling Toxoplasma microneme exocytosis: Cyclic GMP, calcium, and phosphatidic acid
To elicit effective invasion and egress from infected cells, obligate intracellular parasites of
the phylum Apicomplexa rely on the timely and spatially controlled exocytosis of specialized …
the phylum Apicomplexa rely on the timely and spatially controlled exocytosis of specialized …